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MSH6 mutS homolog 6 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715701, updated on 5-Mar-2024

Summary

Official Symbol
MSH6provided by VGNC
Official Full Name
mutS homolog 6provided by VGNC
Primary source
VGNC:VGNC:74934
See related
Ensembl:ENSMMUG00000022842
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See MSH6 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
10
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (60969418..60995316, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (48538694..48564604)

Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671712 Neighboring gene F-box protein 11 Neighboring gene ubiquitin-40S ribosomal protein S27a pseudogene Neighboring gene uncharacterized protein C8orf59 homolog Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of MutSalpha complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
DNA mismatch repair protein Msh6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266076.2NP_001253005.1  DNA mismatch repair protein Msh6

    See identical proteins and their annotated locations for NP_001253005.1

    Status: PROVISIONAL

    Source sequence(s)
    JV046859
    UniProtKB/TrEMBL
    F6UF63, G7NA13
    Related
    ENSMMUP00000030085.2, ENSMMUT00000032156.4
    Conserved Domains (7) summary
    cd05837
    Location:88195
    MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    COG0249
    Location:4071336
    MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
    pfam01624
    Location:407525
    MutS_I; MutS domain I
    pfam05188
    Location:538692
    MutS_II; MutS domain II
    pfam05190
    Location:9321024
    MutS_IV; MutS family domain IV
    pfam05192
    Location:739827
    MutS_III; MutS domain III
    cl21455
    Location:10911313
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041766.1 Reference Mmul_10 Primary Assembly

    Range
    60969418..60995316 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)