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Clmp CXADR-like membrane protein [ Mus musculus (house mouse) ]

Gene ID: 71566, updated on 12-May-2024

Summary

Official Symbol
Clmpprovided by MGI
Official Full Name
CXADR-like membrane proteinprovided by MGI
Primary source
MGI:MGI:1918816
See related
Ensembl:ENSMUSG00000032024 AllianceGenome:MGI:1918816
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ACAM; ASP5; 9030425E11Rik
Summary
Predicted to be involved in digestive tract development. Predicted to be located in bicellular tight junction; cytoplasmic microtubule; and membrane. Is expressed in cerebral cortex; cerebral cortex mantle layer; and cerebral cortex marginal layer. Human ortholog(s) of this gene implicated in intestinal pseudo-obstruction. Orthologous to human CLMP (CXADR like membrane protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 13.4), CNS E18 (RPKM 13.4) and 21 other tissues See more
Orthologs
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Genomic context

See Clmp in Genome Data Viewer
Location:
9 A5.1; 9 21.42 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (40596975..40696849)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (40682123..40785553)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39319 Neighboring gene predicted gene, 35371 Neighboring gene VISTA enhancer mm1624 Neighboring gene STARR-positive B cell enhancer ABC_E10540 Neighboring gene predicted gene, 48293 Neighboring gene predicted gene 16096 Neighboring gene STARR-seq mESC enhancer starr_23871 Neighboring gene STARR-seq mESC enhancer starr_23872 Neighboring gene small nucleolar RNA, C/D box 14C Neighboring gene small nucleolar RNA, C/D box 14D Neighboring gene heat shock protein 8

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (4)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
 
located_in bicellular tight junction ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in postsynaptic membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
CXADR-like membrane protein
Names
CAR-like membrane protein
adipocyte adhesion molecule
adipocyte-specific protein 5
coxsackie- and adenovirus receptor-like membrane protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133733.5NP_598494.2  CXADR-like membrane protein precursor

    See identical proteins and their annotated locations for NP_598494.2

    Status: VALIDATED

    Source sequence(s)
    AC140409, AC158355
    Consensus CDS
    CCDS23082.1
    UniProtKB/Swiss-Prot
    Q8R373, Q920S5
    Related
    ENSMUSP00000034522.8, ENSMUST00000034522.8
    Conserved Domains (2) summary
    smart00410
    Location:143224
    IG_like; Immunoglobulin like
    pfam07686
    Location:28128
    V-set; Immunoglobulin V-set domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    40596975..40696849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510602.5XP_006510665.1  CXADR-like membrane protein isoform X1

    Conserved Domains (2) summary
    smart00409
    Location:169250
    IG; Immunoglobulin
    pfam07686
    Location:54154
    V-set; Immunoglobulin V-set domain
  2. XM_006510603.3XP_006510666.1  CXADR-like membrane protein isoform X2

    Conserved Domains (2) summary
    smart00409
    Location:142223
    IG; Immunoglobulin
    pfam07686
    Location:27127
    V-set; Immunoglobulin V-set domain

RNA

  1. XR_003948007.2 RNA Sequence