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CDK4 cyclin dependent kinase 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715650, updated on 12-Dec-2025
Official Symbol
CDK4provided by VGNC
Official Full Name
cyclin dependent kinase 4provided by VGNC
Primary source
VGNC:VGNC:70980
Locus tag
EGK_03854
See related
Ensembl:ENSMMUG00000023694
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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Try the new Transcripts and proteins table
See CDK4 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 11 NC_133416.1 (64927716..64931828, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (57333997..57338103, complement)

Chromosome 11 - NC_133416.1Genomic Context describing neighboring genes Neighboring gene OS9 endoplasmic reticulum lectin Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Neighboring gene tetraspanin 31 Neighboring gene uncharacterized LOC114671101 Neighboring gene membrane associated ring-CH-type finger 9

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
cyclin-dependent kinase 4
Names
Cell division protein kinase 4
NP_001248276.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261347.2 → NP_001248276.1  cyclin-dependent kinase 4

    See identical proteins and their annotated locations for NP_001248276.1

    Status: PROVISIONAL

    Source sequence(s)
    JV044345
    UniProtKB/TrEMBL
    A0A1D5QJW2, A0A8J8Y3N2, F7HCW9, G7N7H3, I0FIZ0
    Related
    ENSMMUP00000031213.4, ENSMMUT00000033350.4
    Conserved Domains (1) summary
    cl21453
    Location:5 → 295
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133416.1 Reference T2T-MMU8v2.0

    Range
    64927716..64931828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials