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Izumo4 IZUMO family member 4 [ Mus musculus (house mouse) ]

Gene ID: 71564, updated on 26-Sep-2022

Summary

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Official Symbol
Izumo4provided by MGI
Official Full Name
IZUMO family member 4provided by MGI
Primary source
MGI:MGI:1918814
See related
Ensembl:ENSMUSG00000055862 AllianceGenome:MGI:1918814
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9030607L17Rik
Summary
Predicted to be located in extracellular region. Is expressed in dorsal root ganglion; glossopharyngeal ganglion; and trigeminal ganglion. Orthologous to human IZUMO4 (IZUMO family member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 86.3), bladder adult (RPKM 15.5) and 23 other tissues See more
Orthologs
human all
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Genomic context

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See Izumo4 in Genome Data Viewer
Location:
10; 10 C1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80537858..80541216)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80702015..80705382)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene MAP kinase-interacting serine/threonine kinase 2 Neighboring gene MOB kinase activator 3A Neighboring gene adaptor-related protein complex 3, delta 1 subunit Neighboring gene predicted gene, 53592

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
izumo sperm-egg fusion protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027829.3 → NP_082105.3  izumo sperm-egg fusion protein 4 precursor

    See identical proteins and their annotated locations for NP_082105.3

    Status: VALIDATED

    Source sequence(s)
    BF682661, CAAA01118979, CB055593, CF105977
    Consensus CDS
    CCDS35983.1
    UniProtKB/Swiss-Prot
    D3Z690, Q6PEP3
    Related
    ENSMUSP00000151397.2, ENSMUST00000218184.2
    Conserved Domains (1) summary
    pfam15005
    Location:26 → 166
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    80537858..80541216
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017314096.3 → XP_017169585.1  izumo sperm-egg fusion protein 4 isoform X11

    Conserved Domains (1) summary
    pfam15005
    Location:5 → 70
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  2. XM_006514134.3 → XP_006514197.1  izumo sperm-egg fusion protein 4 isoform X1

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 150
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  3. XM_006514136.3 → XP_006514199.1  izumo sperm-egg fusion protein 4 isoform X2

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 150
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  4. XM_036156017.1 → XP_036011910.1  izumo sperm-egg fusion protein 4 isoform X4

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 149
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  5. XM_017314090.2 → XP_017169579.1  izumo sperm-egg fusion protein 4 isoform X3

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 150
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  6. XM_006514138.3 → XP_006514201.1  izumo sperm-egg fusion protein 4 isoform X4

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 149
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  7. XM_017314095.3 → XP_017169584.1  izumo sperm-egg fusion protein 4 isoform X9

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 150
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  8. XM_006514143.3 → XP_006514206.1  izumo sperm-egg fusion protein 4 isoform X9

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 150
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  9. XM_030245283.2 → XP_030101143.1  izumo sperm-egg fusion protein 4 isoform X12

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 150
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  10. XM_006514145.3 → XP_006514208.1  izumo sperm-egg fusion protein 4 isoform X12

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 150
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  11. XM_017314094.2 → XP_017169583.1  izumo sperm-egg fusion protein 4 isoform X8

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 166
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  12. XM_017314092.2 → XP_017169581.1  izumo sperm-egg fusion protein 4 isoform X6

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 166
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  13. XM_036156019.1 → XP_036011912.1  izumo sperm-egg fusion protein 4 isoform X10

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 166
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  14. XM_006514139.4 → XP_006514202.1  izumo sperm-egg fusion protein 4 isoform X5

    Related
    ENSMUSP00000093076.5, ENSMUST00000095426.5
    Conserved Domains (1) summary
    pfam15005
    Location:27 → 166
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  15. XM_036156018.1 → XP_036011911.1  izumo sperm-egg fusion protein 4 isoform X7

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 166
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  16. XM_006514141.3 → XP_006514204.1  izumo sperm-egg fusion protein 4 isoform X7

    Conserved Domains (1) summary
    pfam15005
    Location:27 → 166
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  17. XM_030245284.2 → XP_030101144.1  izumo sperm-egg fusion protein 4 isoform X14

    Conserved Domains (1) summary
    pfam15005
    Location:1 → 70
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

  18. XM_006514146.4 → XP_006514209.1  izumo sperm-egg fusion protein 4 isoform X13

    See identical proteins and their annotated locations for XP_006514209.1

    Conserved Domains (1) summary
    pfam15005
    Location:1 → 54
    IZUMO; Izumo sperm-egg fusion, Ig domain-associated

RNA

  1. XR_001779600.3 RNA Sequence

  2. XR_003948804.1 RNA Sequence

  3. XR_001779602.2 RNA Sequence

  4. XR_001779603.2 RNA Sequence

  5. XR_003948806.1 RNA Sequence

  6. XR_003948805.2 RNA Sequence

  7. XR_001779601.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D3Z690.1 GenPept UniProtKB/Swiss-Prot:D3Z690

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