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AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715504, updated on 10-Feb-2026
Official Symbol
AGAP2provided by VGNC
Official Full Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2provided by VGNC
Primary source
VGNC:VGNC:69620
See related
Ensembl:ENSMMUG00000023690
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
CENTG1
Orthologs
all
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See AGAP2 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 11 NC_133416.1 (64903112..64921666, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (57309381..57327938, complement)

Chromosome 11 - NC_133416.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL13-like Neighboring gene OS9 endoplasmic reticulum lectin Neighboring gene tetraspanin 31 Neighboring gene uncharacterized LOC114671101 Neighboring gene cyclin dependent kinase 4

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
Names
centaurin, gamma 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266854.1 → NP_001253783.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

    See identical proteins and their annotated locations for NP_001253783.1

    Status: PROVISIONAL

    Source sequence(s)
    JV565062
    UniProtKB/TrEMBL
    H9F5U7, I2CTW2
    Related
    ENSMMUP00000066797.1, ENSMMUT00000093708.1
    Conserved Domains (6) summary
    cd04103
    Location:407 → 566
    Centaurin_gamma; Centaurin gamma (CENTG) GTPase
    PRK07764
    Location:83 → 174
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01250
    Location:674 → 914
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:1058 → 1088
    ANK; ANK repeat [structural motif]
    cd08836
    Location:932 → 1039
    ArfGap_AGAP; ArfGAP with GTPase domain, ANK repeat and PH domains
    pfam12796
    Location:1058 → 1148
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133416.1 Reference T2T-MMU8v2.0

    Range
    64903112..64921666 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028829003.2 → XP_028684836.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    F7HCX8, H9Z534
    Related
    ENSMMUP00000064510.1
    Conserved Domains (5) summary
    cd04103
    Location:71 → 230
    Centaurin_gamma; Centaurin gamma (CENTG) GTPase
    cd01250
    Location:338 → 558
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:702 → 732
    ANK; ANK repeat [structural motif]
    cd08836
    Location:576 → 683
    ArfGap_AGAP; ArfGAP with GTPase domain, ANK repeat and PH domains
    pfam12796
    Location:702 → 792
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_028829001.2 → XP_028684834.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    F7HCY1, H9F5U7
    Related
    ENSMMUP00000031206.4
    Conserved Domains (6) summary
    cd04103
    Location:407 → 566
    Centaurin_gamma; Centaurin gamma (CENTG) GTPase
    PRK07764
    Location:83 → 174
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01250
    Location:674 → 894
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:1038 → 1068
    ANK; ANK repeat [structural motif]
    cd08836
    Location:912 → 1019
    ArfGap_AGAP; ArfGAP with GTPase domain, ANK repeat and PH domains
    pfam12796
    Location:1038 → 1128
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
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