SIRT7 sirtuin 7 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: SIRT7provided by VGNC
Official Full Name: sirtuin 7provided by VGNC
Primary source: VGNC:VGNC:77487
See related: Ensembl:ENSMMUG00000012890
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: all
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Genomic context

Location:: chromosome: 16

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2025_08	current	T2T-MMU8v2.0 (GCF_049350105.2)	16	NC_133421.1 (91574972..91581800, complement)
103	previous assembly	Mmul_10 (GCF_003339765.1)	16	NC_041769.1 (78211362..78218283, complement)

Chromosome 16 - NC_133421.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH65676 (e-PCR)
- UniSTS:37993

SIRT7_1731 (e-PCR)
- UniSTS:277714

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables NAD+ binding	IEA Inferred from Electronic Annotation more info	PubMed
enables histone H3K18 deacetylase activity, NAD-dependent	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in chromatin	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NAD-dependent protein deacetylase sirtuin-7

Names: NAD-dependent deacetylase sirtuin-7

NP_001244889.1

EC 2.3.1.286

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001257960.1 → NP_001244889.1 NAD-dependent protein deacetylase sirtuin-7

See identical proteins and their annotated locations for NP_001244889.1

Status: PROVISIONAL

Source sequence(s)

JU334924

UniProtKB/TrEMBL

A0A5F7Z9R1, I0FSG8

Related

ENSMMUP00000061375.1, ENSMMUT00000105150.1

Conserved Domains (2) summary

cd01410
Location:100 → 314

SIRT7; SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent ...

pfam07321
Location:16 → 101

YscO; Type III secretion protein YscO