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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001308022.2 → NP_001294951.1 tensin-1 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR, lacks in-frame exon in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AB209238, AC009469, AF225896, AK300345, AK309785, BC051304, BC116187, BC116188, BQ045472
- Consensus CDS
-
CCDS77529.1
- UniProtKB/Swiss-Prot
-
Q9HBL0
- UniProtKB/TrEMBL
- B7Z6H8, E9PF55, Q0VG54, Q0VG55, Q59G71, Q86VB0
- Related
- ENSP00000408724.1, ENST00000419504.5
- Conserved Domains (4) summary
-
- cd09927
Location:1446 → 1560
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1582 → 1715
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumour-suppressor protein
-
NM_001308023.2 → NP_001294952.1 tensin-1 isoform 3
See identical proteins and their annotated locations for NP_001294952.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, and lacks two consecutive in-frame exons in the central coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AC009469
- Consensus CDS
-
CCDS77528.1
- UniProtKB/TrEMBL
- B2RU35, B7Z6H8, E9PGF5, Q0VG54, Q59G71, Q86VB0
- Related
- ENSP00000406016.1, ENST00000430930.5
- Conserved Domains (4) summary
-
- cd09927
Location:1438 → 1553
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1575 → 1708
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumour-suppressor protein
-
NM_001387777.1 → NP_001374706.1 tensin-1 isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC009469, AC010136
- Related
- ENSP00000498399.1, ENST00000651849.1
-
NM_022648.7 → NP_072174.3 tensin-1 isoform 1
See identical proteins and their annotated locations for NP_072174.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AB209238, AC009469, AF225896, AL706926, BC051304, BC126910, BQ045472
- Consensus CDS
-
CCDS2407.1
- UniProtKB/Swiss-Prot
-
Q9HBL0
- UniProtKB/TrEMBL
- A1L0S7, Q59G71, Q86VB0
- Related
- ENSP00000171887.4, ENST00000171887.8
- Conserved Domains (5) summary
-
- cd09927
Location:1459 → 1574
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00012
Location:77 → 192
- PTPc_DSPc; Protein tyrosine phosphatase, catalytic domain, undefined specificity
- cd01213
Location:1596 → 1729
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:555 → 944
- Atrophin-1; Atrophin-1 family
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p13 Primary Assembly
Genomic
-
NC_000002.12 Reference GRCh38.p13 Primary Assembly
- Range
-
217799789..218002995 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_024453079.1 → XP_024308847.1 tensin-1 isoform X12
- Conserved Domains (6) summary
-
- cd09927
Location:1729 → 1844
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:202 → 317
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1866 → 1999
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- cl00040
Location:34 → 67
- C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
- pfam10409
Location:304 → 430
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:752 → 1167
- Atrophin-1; Atrophin-1 family
-
XM_024453084.1 → XP_024308852.1 tensin-1 isoform X20
- Conserved Domains (5) summary
-
- cd09927
Location:1459 → 1574
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00012
Location:77 → 192
- PTPc_DSPc; Protein tyrosine phosphatase, catalytic domain, undefined specificity
- cd01213
Location:1596 → 1729
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:555 → 944
- Atrophin-1; Atrophin-1 family
-
XM_024453078.1 → XP_024308846.1 tensin-1 isoform X11
- Conserved Domains (5) summary
-
- cd09927
Location:1532 → 1647
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1669 → 1802
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:555 → 970
- Atrophin-1; Atrophin-1 family
-
XM_017004812.1 → XP_016860301.1 tensin-1 isoform X11
- Conserved Domains (5) summary
-
- cd09927
Location:1532 → 1647
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1669 → 1802
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:555 → 970
- Atrophin-1; Atrophin-1 family
-
XM_017004811.1 → XP_016860300.1 tensin-1 isoform X11
- Conserved Domains (5) summary
-
- cd09927
Location:1532 → 1647
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1669 → 1802
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:555 → 970
- Atrophin-1; Atrophin-1 family
-
XM_024453082.1 → XP_024308850.1 tensin-1 isoform X14
- Conserved Domains (5) summary
-
- cd09927
Location:1604 → 1719
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00012
Location:77 → 192
- PTPc_DSPc; Protein tyrosine phosphatase, catalytic domain, undefined specificity
- cd01213
Location:1741 → 1874
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:627 → 1042
- Atrophin-1; Atrophin-1 family
-
XM_024453081.1 → XP_024308849.1 tensin-1 isoform X14
- Conserved Domains (5) summary
-
- cd09927
Location:1604 → 1719
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00012
Location:77 → 192
- PTPc_DSPc; Protein tyrosine phosphatase, catalytic domain, undefined specificity
- cd01213
Location:1741 → 1874
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:627 → 1042
- Atrophin-1; Atrophin-1 family
-
XM_024453080.1 → XP_024308848.1 tensin-1 isoform X13
- Conserved Domains (5) summary
-
- cd09927
Location:1669 → 1784
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:142 → 257
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1806 → 1939
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:244 → 370
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:692 → 1107
- Atrophin-1; Atrophin-1 family
-
XM_024453077.1 → XP_024308845.1 tensin-1 isoform X10
- Conserved Domains (5) summary
-
- cd09927
Location:1451 → 1566
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00012
Location:77 → 192
- PTPc_DSPc; Protein tyrosine phosphatase, catalytic domain, undefined specificity
- cd01213
Location:1588 → 1721
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:555 → 944
- Atrophin-1; Atrophin-1 family
-
XM_024453072.1 → XP_024308840.1 tensin-1 isoform X5
- Conserved Domains (5) summary
-
- cd09927
Location:1548 → 1663
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00012
Location:77 → 192
- PTPc_DSPc; Protein tyrosine phosphatase, catalytic domain, undefined specificity
- cd01213
Location:1685 → 1818
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:571 → 986
- Atrophin-1; Atrophin-1 family
-
XM_024453076.1 → XP_024308844.1 tensin-1 isoform X9
- Conserved Domains (5) summary
-
- cd09927
Location:1510 → 1625
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1647 → 1780
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:844 → 1355
- Atrophin-1; Atrophin-1 family
-
XM_024453075.1 → XP_024308843.1 tensin-1 isoform X8
- Conserved Domains (5) summary
-
- cd09927
Location:1523 → 1638
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1660 → 1793
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:627 → 1016
- Atrophin-1; Atrophin-1 family
-
XM_024453069.1 → XP_024308837.1 tensin-1 isoform X2
- Conserved Domains (5) summary
-
- cd09927
Location:1575 → 1690
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1712 → 1845
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:627 → 1016
- Atrophin-1; Atrophin-1 family
-
XM_024453074.1 → XP_024308842.1 tensin-1 isoform X7
- Conserved Domains (5) summary
-
- cd09927
Location:1539 → 1654
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1676 → 1809
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:627 → 1042
- Atrophin-1; Atrophin-1 family
-
XM_024453071.1 → XP_024308839.1 tensin-1 isoform X4
- Conserved Domains (5) summary
-
- cd09927
Location:1552 → 1667
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1689 → 1822
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:627 → 1042
- Atrophin-1; Atrophin-1 family
-
XM_024453073.1 → XP_024308841.1 tensin-1 isoform X6
- Conserved Domains (5) summary
-
- cd09927
Location:1547 → 1662
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1684 → 1817
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:845 → 1457
- Atrophin-1; Atrophin-1 family
-
XM_024453070.1 → XP_024308838.1 tensin-1 isoform X3
- Conserved Domains (5) summary
-
- cd09927
Location:1560 → 1675
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1697 → 1830
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:627 → 1042
- Atrophin-1; Atrophin-1 family
-
XM_024453068.1 → XP_024308836.1 tensin-1 isoform X1
- Conserved Domains (5) summary
-
- cd09927
Location:1604 → 1718
- SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
- smart00404
Location:77 → 192
- PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
- cd01213
Location:1740 → 1873
- PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
- pfam10409
Location:179 → 305
- PTEN_C2; C2 domain of PTEN tumor-suppressor protein
- cl26464
Location:627 → 1042
- Atrophin-1; Atrophin-1 family
-
XM_017004814.1 → XP_016860303.1 tensin-1 isoform X18
-
XM_017004815.1 → XP_016860304.1 tensin-1 isoform X18
-
XM_017004813.2 → XP_016860302.1 tensin-1 isoform X17
- Related
- ENSP00000480559.1, ENST00000615025.4
-
XM_017004816.2 → XP_016860305.1 tensin-1 isoform X19