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Spaar small regulatory polypeptide of amino acid response [ Mus musculus (house mouse) ]

Gene ID: 71406, updated on 4-May-2024

Summary

Official Symbol
Spaarprovided by MGI
Official Full Name
small regulatory polypeptide of amino acid responseprovided by MGI
Primary source
MGI:MGI:1918656
See related
Ensembl:ENSMUSG00000028475 AllianceGenome:MGI:1918656
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Spar; 5430416O09Rik
Summary
Involved in cellular response to amino acid stimulus; negative regulation of TORC1 signaling; and regulation of skeletal muscle tissue regeneration. Predicted to be located in late endosome membrane. Predicted to be integral component of lysosomal membrane. Predicted to be part of lysosomal proton-transporting V-type ATPase complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; and sensory organ. Orthologous to human SPAAR (small regulatory polypeptide of amino acid response). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in subcutaneous fat pad adult (RPKM 4.1), lung adult (RPKM 3.0) and 16 other tissues See more
Orthologs
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Genomic context

Location:
4 A5; 4 23.05 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (43730045..43732084)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (43730034..43734534)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 13 subfamily J member 1 Neighboring gene STARR-seq mESC enhancer starr_10058 Neighboring gene histidine rich carboxyl terminus 1 Neighboring gene STARR-seq mESC enhancer starr_10059 Neighboring gene predicted gene, 54217 Neighboring gene RIKEN cDNA A630077J23 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General protein information

Preferred Names
small regulatory polypeptide of amino acid response

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001348108.2NP_001335037.1  small regulatory polypeptide of amino acid response

    Status: VALIDATED

    Source sequence(s)
    AL824712
    Consensus CDS
    CCDS89739.1
    UniProtKB/Swiss-Prot
    A0A1B0GSZ0
    Related
    ENSMUSP00000148128.2, ENSMUST00000131248.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    43730045..43732084
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_027789.3: Suppressed sequence

    Description
    NM_027789.3: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.