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CXCR6 C-X-C motif chemokine receptor 6 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713829, updated on 10-Feb-2026
Official Symbol
CXCR6provided by VGNC
Official Full Name
C-X-C motif chemokine receptor 6provided by VGNC
Primary source
VGNC:VGNC:71423
See related
Ensembl:ENSMMUG00000023587
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
Bonzo; CD186; STRL33
Orthologs
all
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See CXCR6 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 2 NC_133407.1 (109294601..109300700)
103 previous assembly Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (101948255..101953190)

Chromosome 2 - NC_133407.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC144339135 Neighboring gene succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial pseudogene Neighboring gene C-C motif chemokine receptor 9 Neighboring gene FYVE and coiled-coil domain autophagy adaptor 1 Neighboring gene nuclear receptor-binding factor 2 pseudogene Neighboring gene X-C motif chemokine receptor 1 Neighboring gene vascular endothelial growth factor receptor 1 pseudogene

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Loss of CXCR6 coreceptor usage characterizes pathogenic lentiviruses. Wetzel KS, et al. PLoS Pathog, 2018 Apr. PMID 29659623, Free PMC Article
  2. Polymorphisms in eight host genes associated with control of HIV replication do not mediate elite control of viral replication in SIV-infected Indian rhesus macaques. Weiler A, et al. Immunogenetics, 2006 Dec. PMID 17106666
  3. Identification and comparison of eleven rhesus macaque chemokine receptors. Margulies BJ, et al. AIDS Res Hum Retroviruses, 2001 Jul 1. PMID 11461684, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables C-C chemokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables C-C chemokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables C-X-C chemokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables coreceptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
C-X-C chemokine receptor type 6
Names
CXC-R6
CXCR-6
G protein-coupled receptor TYMSTR
G-protein coupled receptor STRL33
G-protein coupled receptor bonzo
chemokine (C-X-C motif) receptor 6
chemokine receptor bonzo

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001047141.1 → NP_001040606.1  C-X-C chemokine receptor type 6

    See identical proteins and their annotated locations for NP_001040606.1

    Status: PROVISIONAL

    Source sequence(s)
    AF124380
    UniProtKB/Swiss-Prot
    Q9XT45
    UniProtKB/TrEMBL
    H9Z4H8, Q09H40
    Conserved Domains (1) summary
    pfam00001
    Location:49 → 289
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133407.1 Reference T2T-MMU8v2.0

    Range
    109294601..109300700
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015131078.3 → XP_014986564.1  C-X-C chemokine receptor type 6 isoform X1

    UniProtKB/TrEMBL
    F7BTV1
    Related
    ENSMMUP00000039108.2
    Conserved Domains (1) summary
    pfam00001
    Location:89 → 329
    7tm_1; 7 transmembrane receptor (rhodopsin family)

  2. XM_077990832.1 → XP_077846958.1  C-X-C chemokine receptor type 6 isoform X2

    UniProtKB/Swiss-Prot
    Q9XT45
    UniProtKB/TrEMBL
    H9Z4H8, Q09H40

  3. XM_077990833.1 → XP_077846959.1  C-X-C chemokine receptor type 6 isoform X2

    UniProtKB/Swiss-Prot
    Q9XT45
    UniProtKB/TrEMBL
    H9Z4H8, Q09H40

  4. XM_015131079.3 → XP_014986565.1  C-X-C chemokine receptor type 6 isoform X2

    UniProtKB/Swiss-Prot
    Q9XT45
    UniProtKB/TrEMBL
    H9Z4H8, Q09H40
    Conserved Domains (1) summary
    pfam00001
    Location:49 → 289
    7tm_1; 7 transmembrane receptor (rhodopsin family)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XT45.1 GenPept UniProtKB/Swiss-Prot:Q9XT45

Gene LinkOut

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Research Materials