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Rbks ribokinase [ Mus musculus (house mouse) ]

Gene ID: 71336, updated on 5-Jan-2023

Summary

Official Symbol
Rbksprovided by MGI
Official Full Name
ribokinaseprovided by MGI
Primary source
MGI:MGI:1918586
See related
Ensembl:ENSMUSG00000029136 AllianceGenome:MGI:1918586
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RK; RBSK; 5230400M11Rik
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in D-ribose metabolic process. Predicted to act upstream of or within carbohydrate metabolic process and phosphorylation. Predicted to be located in cytoplasm and nucleus. Orthologous to human RBKS (ribokinase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 4.4), testis adult (RPKM 4.2) and 28 other tissues See more
Orthologs
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Genomic context

See Rbks in Genome Data Viewer
Location:
5; 5 B1
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31781783..31855042, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (31624439..31697649, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene expressed sequence AI839979 Neighboring gene predicted gene, 38424 Neighboring gene mitochondrial ribosomal protein L33 Neighboring gene microRNA 3473e Neighboring gene BRISC and BRCA1 A complex member 2 Neighboring gene predicted gene, 52770 Neighboring gene microRNA 12198 Neighboring gene predicted gene, 40277

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphotransferase activity, alcohol group as acceptor IEA
Inferred from Electronic Annotation
more info
 
enables ribokinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in D-ribose metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within carbohydrate phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in pentose-phosphate shunt IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytosol ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ribokinase
NP_694876.1
XP_006504176.1
XP_006504177.1
XP_011239073.1
XP_030110668.1
XP_036021384.1
XP_036021385.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153196.1NP_694876.1  ribokinase

    See identical proteins and their annotated locations for NP_694876.1

    Status: PROVISIONAL

    Source sequence(s)
    BC023339
    Consensus CDS
    CCDS19187.1
    UniProtKB/Swiss-Prot
    Q8R1Q9
    Related
    ENSMUSP00000031018.8, ENSMUST00000031018.10
    Conserved Domains (1) summary
    TIGR02152
    Location:23319
    D_ribokin_bact; ribokinase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    31781783..31855042 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504114.3XP_006504177.1  ribokinase isoform X3

    Conserved Domains (1) summary
    cl00192
    Location:23264
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
  2. XM_030254808.2XP_030110668.1  ribokinase isoform X4

    Conserved Domains (1) summary
    cl00192
    Location:1170
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
  3. XM_036165492.1XP_036021385.1  ribokinase isoform X4

    Conserved Domains (1) summary
    cl00192
    Location:1170
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
  4. XM_036165491.1XP_036021384.1  ribokinase isoform X4

    Conserved Domains (1) summary
    cl00192
    Location:1170
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
  5. XM_006504113.5XP_006504176.1  ribokinase isoform X2

    Conserved Domains (1) summary
    cl00192
    Location:23266
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
  6. XM_011240771.4XP_011239073.1  ribokinase isoform X1

    Conserved Domains (1) summary
    cl00192
    Location:23266
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

RNA

  1. XR_376828.4 RNA Sequence