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CBLC Cbl proto-oncogene C [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713112, updated on 10-Feb-2026
Official Symbol
CBLCprovided by VGNC
Official Full Name
Cbl proto-oncogene Cprovided by VGNC
Primary source
VGNC:VGNC:108489
Locus tag
EGK_10730
See related
Ensembl:ENSMMUG00000049451
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See CBLC in Genome Data Viewer
Location:
chromosome: 19
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 19 NC_133424.1 (57282652..57312406)
103 previous assembly Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (44814744..44838016)

Chromosome 19 - NC_133424.1Genomic Context describing neighboring genes Neighboring gene BCL3 transcription coactivator Neighboring gene small nucleolar RNA SNORA70 Neighboring gene uncharacterized LOC144337186 Neighboring gene uncharacterized LOC144337185 Neighboring gene basal cell adhesion molecule

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin-protein ligase CBL-C
Names
Cas-Br-M (murine) ecotropic retroviral transforming sequence c
Cbl proto-oncogene, E3 ubiquitin protein ligase C
XP_001109370.1
XP_014979724.1
XP_028694946.1
XP_077836490.1
XP_077836491.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133424.1 Reference T2T-MMU8v2.0

    Range
    57282652..57312406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_077980365.1 → XP_077836491.1  E3 ubiquitin-protein ligase CBL-C isoform X2

  2. XM_015124238.3 → XP_014979724.1  E3 ubiquitin-protein ligase CBL-C isoform X3

    UniProtKB/TrEMBL
    A0A5F8AHX9
    Related
    ENSMMUP00000076595.1
    Conserved Domains (3) summary
    pfam02262
    Location:16 → 145
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:149 → 232
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
    cl15255
    Location:226 → 331
    SH2; Src homology 2 (SH2) domain

  3. XM_077980364.1 → XP_077836490.1  E3 ubiquitin-protein ligase CBL-C isoform X1

    UniProtKB/TrEMBL
    A0A5F8A6T2, A0A8J8XPX7, F7FKP6

  4. XM_001109370.5 → XP_001109370.1  E3 ubiquitin-protein ligase CBL-C isoform X1

    See identical proteins and their annotated locations for XP_001109370.1

    UniProtKB/TrEMBL
    A0A5F8A6T2, A0A8J8XPX7, F7FKP6
    Related
    ENSMMUP00000072666.1
    Conserved Domains (4) summary
    cd09920
    Location:226 → 322
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd00162
    Location:351 → 393
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam02262
    Location:16 → 145
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:149 → 232
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  5. XM_028839113.2 → XP_028694946.1  E3 ubiquitin-protein ligase CBL-C isoform X2

    Conserved Domains (4) summary
    cd09920
    Location:226 → 322
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    pfam02262
    Location:16 → 145
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    cd16710
    Location:345 → 397
    RING-HC_Cbl-c; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-c and similar proteins
    pfam02761
    Location:149 → 232
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

RNA

  1. XR_013409895.1 RNA Sequence

  2. XR_003724951.2 RNA Sequence

Nucleotide Protein
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