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SPG21 SPG21 abhydrolase domain containing, maspardin [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 712815, updated on 16-Apr-2026
Official Symbol
SPG21provided by VGNC
Official Full Name
SPG21 abhydrolase domain containing, maspardinprovided by VGNC
Primary source
VGNC:VGNC:77970
See related
Ensembl:ENSMMUG00000010949
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See SPG21 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 7 NC_133412.1 (42383209..42412199, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (41495380..41523700, complement)

Chromosome 7 - NC_133412.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC144329926 Neighboring gene ankyrin repeat and death domain containing 1A Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene transmembrane protein 126A pseudogene Neighboring gene SLC51 subunit beta Neighboring gene RAS like family 12

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CD4 receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in trans-Golgi network transport vesicle IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
maspardin
Names
SPG21, maspardin
spastic paraplegia 21 (autosomal recessive, Mast syndrome)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001194890.3NP_001181819.1  maspardin

    See identical proteins and their annotated locations for NP_001181819.1

    Status: PROVISIONAL

    Source sequence(s)
    JBMGST020000007
    UniProtKB/TrEMBL
    G7MXU0

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133412.1 Reference T2T-MMU8v2.0

    Range
    42383209..42412199 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015142466.3XP_014997952.3  maspardin isoform X1

    UniProtKB/TrEMBL
    A0A5F8AC91
  2. XM_001101919.5XP_001101919.2  maspardin isoform X2

    See identical proteins and their annotated locations for XP_001101919.2

    UniProtKB/TrEMBL
    A0A1D5QGQ8, A0A1D5QIQ0, F7GGK1, G7MXU0
    Related
    ENSMMUP00000014361.4
    Conserved Domains (2) summary
    pfam12697
    Location:46266
    Abhydrolase_6; Alpha/beta hydrolase family
    cl21494
    Location:45147
    Abhydrolase; alpha/beta hydrolases
  3. XM_077938425.1XP_077794551.1  maspardin isoform X2

    UniProtKB/TrEMBL
    A0A1D5QGQ8, A0A1D5QIQ0, F7GGK1, G7MXU0
  4. XM_077938426.1XP_077794552.1  maspardin isoform X2

    UniProtKB/TrEMBL
    A0A1D5QGQ8, A0A1D5QIQ0, F7GGK1, G7MXU0