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Sdhaf3 succinate dehydrogenase complex assembly factor 3 [ Mus musculus (house mouse) ]

Gene ID: 71238, updated on 30-Apr-2024

Summary

Official Symbol
Sdhaf3provided by MGI
Official Full Name
succinate dehydrogenase complex assembly factor 3provided by MGI
Primary source
MGI:MGI:1913288
See related
Ensembl:ENSMUSG00000042505 AllianceGenome:MGI:1913288
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Acn9; 0610005M07Rik; 4933430A16Rik
Summary
Predicted to be involved in mitochondrial respiratory chain complex II assembly and succinate metabolic process. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial intermembrane space. Orthologous to human SDHAF3 (succinate dehydrogenase complex assembly factor 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 3.0), CNS E14 (RPKM 2.9) and 26 other tissues See more
Orthologs
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Genomic context

See Sdhaf3 in Genome Data Viewer
Location:
6 A1; 6 2.83 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (6956004..7039661)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (6955971..7039661)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53323 Neighboring gene STARR-seq mESC enhancer starr_15088 Neighboring gene predicted gene, 22155 Neighboring gene centromere protein E pseudogene Neighboring gene STARR-seq mESC enhancer starr_15089 Neighboring gene predicted gene, 19272

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex II assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in succinate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial intermembrane space ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
succinate dehydrogenase assembly factor 3, mitochondrial
Names
ACN9 homolog
SDH assembly factor 3
protein ACN9 homolog, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077713.2NP_001071181.1  succinate dehydrogenase assembly factor 3, mitochondrial isoform b precursor

    See identical proteins and their annotated locations for NP_001071181.1

    Status: VALIDATED

    Source sequence(s)
    AC122240, AC146599
    Consensus CDS
    CCDS39423.1
    UniProtKB/Swiss-Prot
    Q8BQU3, Q8BT21
    UniProtKB/TrEMBL
    Q0VF92, Q3V4A6
    Related
    ENSMUSP00000040935.5, ENSMUST00000040826.6
    Conserved Domains (1) summary
    pfam13233
    Location:9105
    Complex1_LYR_2; Complex1_LYR-like
  2. NM_001417719.1NP_001404648.1  succinate dehydrogenase assembly factor 3, mitochondrial isoform a precursor

    Status: VALIDATED

    Source sequence(s)
    AC122240, AC146599
  3. NM_001417720.1NP_001404649.1  succinate dehydrogenase assembly factor 3, mitochondrial isoform c precursor

    Status: VALIDATED

    Source sequence(s)
    AC122240, AC146599
  4. NM_001417721.1NP_001404650.1  succinate dehydrogenase assembly factor 3, mitochondrial isoform c precursor

    Status: VALIDATED

    Source sequence(s)
    AC122240

RNA

  1. NR_184564.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122240
    Related
    ENSMUST00000123848.2
  2. NR_184565.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122240, AC146599

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    6956004..7039661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)