U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp689 zinc finger protein 689 [ Mus musculus (house mouse) ]

Gene ID: 71131, updated on 8-Dec-2022

Summary

Official Symbol
Zfp689provided by MGI
Official Full Name
zinc finger protein 689provided by MGI
Primary source
MGI:MGI:1918381
See related
Ensembl:ENSMUSG00000048921 AllianceGenome:MGI:1918381
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf689; 4933416E05Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within skeletal muscle cell differentiation. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and respiratory system. Orthologous to human ZNF689 (zinc finger protein 689). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 5.6), limb E14.5 (RPKM 4.6) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Zfp689 in Genome Data Viewer
Location:
7; 7 F3
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127041308..127048330, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127442136..127449158, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene myeloma-overexpressed gene 2 protein homolog Neighboring gene zinc finger protein 688 Neighboring gene proline rich 14 Neighboring gene fibrosin Neighboring gene microRNA 7060

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables histone binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175163.3NP_780372.2  zinc finger protein 689

    See identical proteins and their annotated locations for NP_780372.2

    Status: VALIDATED

    Source sequence(s)
    AC136146, AK028417, AK051667, BB570116, BU054587, CO041951
    Consensus CDS
    CCDS21867.1
    UniProtKB/Swiss-Prot
    Q8BKK5, Q8C1C6
    Related
    ENSMUSP00000056610.5, ENSMUST00000053392.11
    Conserved Domains (5) summary
    smart00349
    Location:2988
    KRAB; krueppel associated box
    COG5048
    Location:171466
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:263283
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2968
    KRAB; KRAB box
    pfam13465
    Location:303328
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    127041308..127048330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)