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SMPD1 sphingomyelin phosphodiesterase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 711248, updated on 8-Apr-2026
Official Symbol
SMPD1provided by VGNC
Official Full Name
sphingomyelin phosphodiesterase 1provided by VGNC
Primary source
VGNC:VGNC:77659
See related
Ensembl:ENSMMUG00000007717
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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Try the new Transcripts and proteins table
See SMPD1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 14 NC_133419.1 (59390004..59394512, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (59545857..59550541, complement)

Chromosome 14 - NC_133419.1Genomic Context describing neighboring genes Neighboring gene hemopexin Neighboring gene amyloid beta precursor protein binding family B member 1 Neighboring gene uncharacterized LOC106993347 Neighboring gene V-type proton ATPase subunit E 1 pseudogene Neighboring gene caveolae associated protein 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acid sphingomyelin phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingomyelin catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
sphingomyelin phosphodiesterase
Names
sphingomyelin phosphodiesterase 1, acid lysosomal
XP_001110212.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133419.1 Reference T2T-MMU8v2.0

    Range
    59390004..59394512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001110212.5 → XP_001110212.1  sphingomyelin phosphodiesterase

    See identical proteins and their annotated locations for XP_001110212.1

    UniProtKB/TrEMBL
    F7C9N4, H9ZCN4
    Related
    ENSMMUP00000010133.2
    Conserved Domains (3) summary
    smart00741
    Location:87 → 160
    SapB; Saposin (B) Domains
    cd00842
    Location:201 → 496
    MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain
    pfam00149
    Location:254 → 461
    Metallophos; Calcineurin-like phosphoesterase
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials