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KLF4 KLF transcription factor 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 711169, updated on 12-Dec-2025
Official Symbol
KLF4provided by VGNC
Official Full Name
KLF transcription factor 4provided by VGNC
Primary source
VGNC:VGNC:74029
See related
Ensembl:ENSMMUG00000006088
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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Try the new Transcripts and proteins table
See KLF4 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 15 NC_133420.1 (50900572..50905425)
103 previous assembly Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (35397811..35402749)

Chromosome 15 - NC_133420.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC144334854 Neighboring gene uncharacterized LOC144334853 Neighboring gene peptidyl-prolyl cis-trans isomerase A-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC144334877 Neighboring gene RAD23 homolog B, nucleotide excision repair protein

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Liu H, et al. Cell Stem Cell, 2008 Dec 4. PMID 19041774
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
Krueppel-like factor 4
Names
Kruppel like factor 4

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142793.2 → NP_001136265.1  Krueppel-like factor 4

    See identical proteins and their annotated locations for NP_001136265.1

    Status: VALIDATED

    Source sequence(s)
    FJ375752, JV727062, JV727063
    UniProtKB/TrEMBL
    B8XIA4, F6VVB3, G7NEK6
    Related
    ENSMMUP00000007996.3, ENSMMUT00000008508.4
    Conserved Domains (4) summary
    COG5048
    Location:391 → 474
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:398 → 420
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:442 → 467
    zf-H2C2_2; Zinc-finger double domain
    cd21582
    Location:7 → 396
    KLF4_N; N-terminal domain of Kruppel-like factor 4

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133420.1 Reference T2T-MMU8v2.0

    Range
    50900572..50905425
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028834359.2 → XP_028690192.1  Krueppel-like factor 4 isoform X1

    UniProtKB/TrEMBL
    G7NEK6
    Conserved Domains (3) summary
    COG5048
    Location:424 → 507
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:431 → 453
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:475 → 500
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials