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FXR1 FMR1 autosomal homolog 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 710170, updated on 17-Aug-2024

Summary

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Official Symbol
FXR1provided by VGNC
Official Full Name
FMR1 autosomal homolog 1provided by VGNC
Primary source
VGNC:VGNC:84179
See related
Ensembl:ENSMMUG00000012105
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See FXR1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
18
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (86147646..86217006)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (112146132..112217196, complement)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106996992 Neighboring gene 60S ribosomal protein L32 pseudogene Neighboring gene uncharacterized LOC114676301 Neighboring gene DnaJ heat shock protein family (Hsp40) member C19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterograde axonal transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendritic spine development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of filopodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mRNA stability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of modification of synaptic structure IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of translation at postsynapse, modulating synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic filopodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine neck IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fragile X mental retardation syndrome-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    86147646..86217006
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015131559.2 → XP_014987045.2  fragile X mental retardation syndrome-related protein 1 isoform X1

    UniProtKB/TrEMBL
    F6W8C6
    Conserved Domains (6) summary
    smart00322
    Location:344 → 403
    KH; K homology RNA-binding domain
    pfam12235
    Location:477 → 590
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:614 → 686
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:733 → 799
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    pfam00013
    Location:409 → 475
    KH_1; KH domain
    pfam05641
    Location:185 → 240
    Agenet; Agenet domain

  2. XM_015131560.2 → XP_014987046.2  fragile X mental retardation syndrome-related protein 1 isoform X2

    UniProtKB/TrEMBL
    F6W8C6
    Related
    ENSMMUP00000038773.3, ENSMMUT00000045729.3
    Conserved Domains (6) summary
    smart00322
    Location:344 → 403
    KH; K homology RNA-binding domain
    pfam12235
    Location:477 → 590
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:614 → 687
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:706 → 772
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    pfam00013
    Location:409 → 475
    KH_1; KH domain
    pfam05641
    Location:185 → 240
    Agenet; Agenet domain

  3. XM_015131563.2 → XP_014987049.2  fragile X mental retardation syndrome-related protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A5F8A267
    Related
    ENSMMUP00000070991.1, ENSMMUT00000092481.1
    Conserved Domains (5) summary
    smart00322
    Location:344 → 403
    KH; K homology RNA-binding domain
    pfam12235
    Location:477 → 590
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:614 → 687
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam00013
    Location:409 → 475
    KH_1; KH domain
    pfam05641
    Location:185 → 240
    Agenet; Agenet domain

  4. XM_015131561.2 → XP_014987047.2  fragile X mental retardation syndrome-related protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A5K1UD59
    Related
    ENSMMUP00000038775.3, ENSMMUT00000045731.3
    Conserved Domains (6) summary
    smart00322
    Location:344 → 403
    KH; K homology RNA-binding domain
    pfam12235
    Location:477 → 561
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:585 → 657
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:704 → 770
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    pfam00013
    Location:409 → 475
    KH_1; KH domain
    pfam05641
    Location:185 → 240
    Agenet; Agenet domain

  5. XM_001098757.4 → XP_001098757.4  fragile X mental retardation syndrome-related protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A5K1UD59
    Conserved Domains (6) summary
    smart00322
    Location:344 → 403
    KH; K homology RNA-binding domain
    pfam12235
    Location:477 → 561
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:585 → 658
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:677 → 743
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    pfam00013
    Location:409 → 475
    KH_1; KH domain
    pfam05641
    Location:185 → 240
    Agenet; Agenet domain

  6. XM_015131564.2 → XP_014987050.2  fragile X mental retardation syndrome-related protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A5F8A267
    Conserved Domains (5) summary
    smart00322
    Location:344 → 403
    KH; K homology RNA-binding domain
    pfam12235
    Location:477 → 561
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:585 → 658
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam00013
    Location:409 → 475
    KH_1; KH domain
    pfam05641
    Location:185 → 240
    Agenet; Agenet domain

  7. XM_028843875.1 → XP_028699708.1  fragile X mental retardation syndrome-related protein 1 isoform X7

    UniProtKB/TrEMBL
    F7H8W8, F7H8X0, H9EN89, H9EN90
    Related
    ENSMMUP00000015875.4, ENSMMUT00000016950.4
    Conserved Domains (7) summary
    pfam12235
    Location:269 → 351
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:377 → 450
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:469 → 535
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    cd22504
    Location:38 → 114
    KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22507
    Location:133 → 195
    KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22510
    Location:196 → 273
    KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cl02573
    Location:1 → 41
    Tudor_SF; Tudor domain superfamily
Nucleotide Protein
Heading Accession and Version

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