U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PRKDC protein kinase, DNA-activated, catalytic subunit [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 708029, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
PRKDCprovided by VGNC
Official Full Name
protein kinase, DNA-activated, catalytic subunitprovided by VGNC
Primary source
VGNC:VGNC:76418
See related
Ensembl:ENSMMUG00000015347
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 8
Exon count:
86
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (48331662..48521183, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (45287699..45476950, complement)

Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene scaffold protein involved in DNA repair Neighboring gene U6 spliceosomal RNA Neighboring gene CCAAT enhancer binding protein delta Neighboring gene U6 spliceosomal RNA Neighboring gene minichromosome maintenance complex component 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via nonhomologous end joining IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immunoglobulin V(D)J recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to DNA damage IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
DNA-dependent protein kinase catalytic subunit
Names
protein kinase, DNA-activated, catalytic polypeptide
XP_015000813.1
XP_015000814.1
XP_015000815.1
XP_015000816.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041761.1 Reference Mmul_10 Primary Assembly

    Range
    48331662..48521183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015145327.1 → XP_015000813.1  DNA-dependent protein kinase catalytic subunit isoform X1

    UniProtKB/TrEMBL
    G7MZ94
    Conserved Domains (4) summary
    cd05172
    Location:3720 → 4016
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:3024 → 3471
    FAT; FAT domain
    pfam02260
    Location:4098 → 4129
    FATC; FATC domain
    pfam08163
    Location:1815 → 2202
    NUC194; NUC194 domain

  2. XM_015145329.2 → XP_015000815.1  DNA-dependent protein kinase catalytic subunit isoform X3

    UniProtKB/TrEMBL
    H9F7A9
    Conserved Domains (4) summary
    cd05172
    Location:3720 → 3985
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:3024 → 3471
    FAT; FAT domain
    pfam02260
    Location:4067 → 4098
    FATC; FATC domain
    pfam08163
    Location:1815 → 2202
    NUC194; NUC194 domain

  3. XM_015145330.2 → XP_015000816.1  DNA-dependent protein kinase catalytic subunit isoform X4

    UniProtKB/TrEMBL
    F6SNY4, H9F7A9
    Related
    ENSMMUP00000020136.4, ENSMMUT00000021529.4
    Conserved Domains (4) summary
    cd05172
    Location:3719 → 3984
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:3023 → 3470
    FAT; FAT domain
    pfam02260
    Location:4066 → 4097
    FATC; FATC domain
    pfam08163
    Location:1815 → 2202
    NUC194; NUC194 domain

  4. XM_015145328.2 → XP_015000814.1  DNA-dependent protein kinase catalytic subunit isoform X2

    UniProtKB/TrEMBL
    F6SP41, G7MZ94
    Related
    ENSMMUP00000020132.3, ENSMMUT00000021524.4
    Conserved Domains (4) summary
    cd05172
    Location:3719 → 4015
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:3023 → 3470
    FAT; FAT domain
    pfam02260
    Location:4097 → 4128
    FATC; FATC domain
    pfam08163
    Location:1815 → 2202
    NUC194; NUC194 domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.