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PRKDC protein kinase, DNA-activated, catalytic subunit [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 708029, updated on 21-Jun-2018

Summary

Gene symbol
PRKDC
Gene description
protein kinase, DNA-activated, catalytic subunit
See related
Ensembl:ENSMMUG00000015347
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs

Genomic context

See PRKDC in Genome Data Viewer
Location:
chromosome: 8
Exon count:
86
Annotation release Status Assembly Chr Location
102 current Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (45287699..45476950, complement)
Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 8 NC_007865.1 (50295889..50484923, complement)

Chromosome 8 - NC_027900.1Genomic Context describing neighboring genes Neighboring gene scaffold protein involved in DNA repair Neighboring gene 40S ribosomal protein S4, X isoform-like Neighboring gene CCAAT enhancer binding protein delta Neighboring gene minichromosome maintenance complex component 4 Neighboring gene ubiquitin conjugating enzyme E2 V2

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Cell cycle, organism-specific biosystem (from KEGG)
    Cell cycle, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
  • Cell cycle, conserved biosystem (from KEGG)
    Cell cycle, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
  • DNA-PK complex, organism-specific biosystem (from KEGG)
    DNA-PK complex, organism-specific biosystemStructural complex; Genetic information processing; Repair system
  • DNA-PK complex, conserved biosystem (from KEGG)
    DNA-PK complex, conserved biosystemStructural complex; Genetic information processing; Repair system
  • Non-homologous end-joining, organism-specific biosystem (from KEGG)
    Non-homologous end-joining, organism-specific biosystemNonhomologous end joining (NHEJ) eliminates DNA double-strand breaks (DSBs) by direct ligation. NHEJ involves binding of the KU heterodimer to double-stranded DNA ends, recruitment of DNA-PKcs (MRX c...
  • Non-homologous end-joining, conserved biosystem (from KEGG)
    Non-homologous end-joining, conserved biosystemNonhomologous end joining (NHEJ) eliminates DNA double-strand breaks (DSBs) by direct ligation. NHEJ involves binding of the KU heterodimer to double-stranded DNA ends, recruitment of DNA-PKcs (MRX c...

General gene information

Markers

Homology

General protein information

Preferred Names
DNA-dependent protein kinase catalytic subunit
Names
protein kinase, DNA-activated, catalytic polypeptide
XP_015000813.1
XP_015000814.1
XP_015000815.1
XP_015000816.1

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_8.0.1 Primary Assembly

Genomic

  1. NC_027900.1 Reference Mmul_8.0.1 Primary Assembly

    Range
    45287699..45476950 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015145330.1XP_015000816.1  DNA-dependent protein kinase catalytic subunit isoform X4

    Related
    ENSMMUP00000020136.3, ENSMMUT00000021529.3
    Conserved Domains (4) summary
    cd05172
    Location:37193984
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:30233470
    FAT; FAT domain
    pfam02260
    Location:40664097
    FATC; FATC domain
    pfam08163
    Location:18152202
    NUC194; NUC194 domain
  2. XM_015145328.1XP_015000814.1  DNA-dependent protein kinase catalytic subunit isoform X2

    UniProtKB/TrEMBL
    F6SP41
    Related
    ENSMMUP00000020132.3, ENSMMUT00000021524.3
    Conserved Domains (4) summary
    cd05172
    Location:37194015
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:30233470
    FAT; FAT domain
    pfam02260
    Location:40974128
    FATC; FATC domain
    pfam08163
    Location:18152202
    NUC194; NUC194 domain
  3. XM_015145329.1XP_015000815.1  DNA-dependent protein kinase catalytic subunit isoform X3

    Conserved Domains (4) summary
    cd05172
    Location:37203985
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:30243471
    FAT; FAT domain
    pfam02260
    Location:40674098
    FATC; FATC domain
    pfam08163
    Location:18152202
    NUC194; NUC194 domain
  4. XM_015145327.1XP_015000813.1  DNA-dependent protein kinase catalytic subunit isoform X1

    Conserved Domains (4) summary
    cd05172
    Location:37204016
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:30243471
    FAT; FAT domain
    pfam02260
    Location:40984129
    FATC; FATC domain
    pfam08163
    Location:18152202
    NUC194; NUC194 domain
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