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Cep192 centrosomal protein 192 [ Mus musculus (house mouse) ]

Gene ID: 70799, updated on 25-Jun-2024

Summary

Official Symbol
Cep192provided by MGI
Official Full Name
centrosomal protein 192provided by MGI
Primary source
MGI:MGI:1918049
See related
Ensembl:ENSMUSG00000024542 AllianceGenome:MGI:1918049
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4631422C13Rik; D430014P18Rik
Summary
Predicted to enable phosphatase binding activity and protein kinase binding activity. Acts upstream of or within response to bacterium. Located in cytoplasm and pericentriolar material. Orthologous to human CEP192 (centrosomal protein 192). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 7.7), limb E14.5 (RPKM 5.8) and 25 other tissues See more
Orthologs
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Genomic context

See Cep192 in Genome Data Viewer
Location:
18 E1- E2; 18 40.11 cM
Exon count:
48
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (67933124..68018241)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (67800054..67885170)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930549G23 gene Neighboring gene STARR-positive B cell enhancer ABC_E11001 Neighboring gene STARR-positive B cell enhancer ABC_E1518 Neighboring gene predicted gene, 26910 Neighboring gene STARR-positive B cell enhancer ABC_E11662 Neighboring gene SEH1-like (S. cerevisiae Neighboring gene STARR-seq mESC enhancer starr_44916 Neighboring gene STARR-seq mESC enhancer starr_44917 Neighboring gene STARR-seq mESC enhancer starr_44919 Neighboring gene tubulin, alpha 1B pseudogene Neighboring gene STARR-seq mESC enhancer starr_44922 Neighboring gene low density lipoprotein receptor class A domain containing 4 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:68126707-68126976 Neighboring gene predicted gene, 52336

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centriole ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in pericentriolar material IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in pericentriolar material IDA
Inferred from Direct Assay
more info
PubMed 
located_in procentriole ISO
Inferred from Sequence Orthology
more info
 
part_of procentriole replication complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
centrosomal protein of 192 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027556.1NP_081832.1  centrosomal protein of 192 kDa

    Status: VALIDATED

    Source sequence(s)
    AC127236, AK052420, AK158414, BC064462, BE982606, CD538408, CK391255, CK639048, CO045915
    Consensus CDS
    CCDS50313.1
    UniProtKB/TrEMBL
    E9Q4Y4
    Related
    ENSMUSP00000025425.6, ENSMUST00000025425.7
    Conserved Domains (1) summary
    cl13764
    Location:16361703
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    67933124..68018241
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526241.3XP_006526304.1  centrosomal protein of 192 kDa isoform X1

    See identical proteins and their annotated locations for XP_006526304.1

    Conserved Domains (2) summary
    pfam08626
    Location:16511772
    TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
    cl13764
    Location:16361703
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
  2. XM_011247001.4XP_011245303.1  centrosomal protein of 192 kDa isoform X5

    Conserved Domains (2) summary
    pfam08626
    Location:16511772
    TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
    cl13764
    Location:16361703
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
  3. XM_006526243.4XP_006526306.1  centrosomal protein of 192 kDa isoform X2

    Conserved Domains (2) summary
    pfam08626
    Location:16081729
    TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
    cl13764
    Location:15931660
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
  4. XM_006526242.3XP_006526305.1  centrosomal protein of 192 kDa isoform X1

    See identical proteins and their annotated locations for XP_006526305.1

    Conserved Domains (2) summary
    pfam08626
    Location:16511772
    TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
    cl13764
    Location:16361703
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
  5. XM_036161275.1XP_036017168.1  centrosomal protein of 192 kDa isoform X3

    Conserved Domains (1) summary
    cl13764
    Location:14061473
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
  6. XM_011247000.4XP_011245302.1  centrosomal protein of 192 kDa isoform X4

    Conserved Domains (2) summary
    pfam08626
    Location:10191140
    TRAPPC9-Trs120; Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit
    cl13764
    Location:10041071
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin