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Ggnbp1 gametogenetin binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 70772, updated on 5-Aug-2018

Summary

Official Symbol
Ggnbp1provided by MGI
Official Full Name
gametogenetin binding protein 1provided by MGI
Primary source
MGI:MGI:3055306
See related
Ensembl:ENSMUSG00000048731 Vega:OTTMUSG00000031014
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mdf; 0610031G08Rik
Expression
Biased expression in testis adult (RPKM 178.0) and kidney adult (RPKM 10.5) See more

Genomic context

See Ggnbp1 in Genome Data Viewer
Location:
17; 17 A3.3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (27018035..27036378)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (27166204..27173323)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene synaptic Ras GTPase activating protein 1 homolog (rat) Neighboring gene microRNA 3083 Neighboring gene zinc finger and BTB domain containing 9 Neighboring gene BCL2-antagonist/killer 1 Neighboring gene inositol 1,4,5-triphosphate receptor 3 Neighboring gene microRNA 7677 Neighboring gene inositol 1,4,5-triphosphate receptor 3, opposite strand

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: Zbtb9

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
thiol-dependent ubiquitin-specific protease activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
endosome organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial fission IDA
Inferred from Direct Assay
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
protein K48-linked deubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein K63-linked deubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein deubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extrinsic component of endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extrinsic component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
midbody IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
gametogenetin-binding protein 1
Names
deubiquitinating enzyme Usp15
gametogenin binding protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001251881.1NP_001238810.1  gametogenetin-binding protein 1 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon and includes two alternate exons in the 5' UTR and CDS, compared to variant 1. It encodes isoform b, which is shorter and has a distinct N-terminus, compared to isoform a.
    Source sequence(s)
    AA388242, CF585840, CO041745
    Consensus CDS
    CCDS57061.1
    UniProtKB/TrEMBL
    D3Z3W4
    Related
    ENSMUSP00000113880.1, OTTMUSP00000040499, ENSMUST00000122106.7, OTTMUST00000076820
    Conserved Domains (1) summary
    pfam14836
    Location:173260
    Ubiquitin_3; Ubiquitin-like domain
  2. NM_027544.2NP_081820.2  gametogenetin-binding protein 1 isoform a

    See identical proteins and their annotated locations for NP_081820.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK077129, AY141192, BB018101
    Consensus CDS
    CCDS28559.1
    UniProtKB/Swiss-Prot
    Q6K1E7
    Related
    ENSMUSP00000051800.6, OTTMUSP00000040498, ENSMUST00000053683.6, OTTMUST00000076819
    Conserved Domains (1) summary
    pfam14836
    Location:281368
    Ubiquitin_3; Ubiquitin-like domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    27018035..27036378
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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