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TIA1 TIA1 cytotoxic granule associated RNA binding protein [ Homo sapiens (human) ]

Gene ID: 7072, updated on 19-Aug-2018

Summary

Official Symbol
TIA1provided by HGNC
Official Full Name
TIA1 cytotoxic granule associated RNA binding proteinprovided by HGNC
Primary source
HGNC:HGNC:11802
See related
Ensembl:ENSG00000116001 MIM:603518; Vega:OTTHUMG00000129644
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
WDM; TIA-1
Summary
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]
Expression
Ubiquitous expression in endometrium (RPKM 25.4), ovary (RPKM 18.9) and 25 other tissues See more
Orthologs

Genomic context

See TIA1 in Genome Data Viewer
Location:
2p13.3
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (70209444..70248793, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (70436576..70475886, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1816 Neighboring gene chromosome 2 open reading frame 42 Neighboring gene transfer RNA-Gly (CCC) 2-1 Neighboring gene microRNA 1285-2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Welander distal myopathy
MedGen: C0221054 OMIM: 604454 GeneReviews: Not available
Compare labs

NHGRI GWAS Catalog

Description
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
NHGRI GWA Catalog

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat co-localizes with TIA1 in cytoplasmic stress granules under stress conditions PubMed

Go to the HIV-1, Human Interaction Database

Pathways from BioSystems

  • FGFR2 alternative splicing, organism-specific biosystem (from REACTOME)
    FGFR2 alternative splicing, organism-specific biosystemAlternative splicing of the FGFR2 nascent mRNA generates an epithelial specific isoform (FGFR2 IIIb) and a mesenchymal specific isoform (FGFR2 IIIc). The inclusion of exon 8 in FGFR2 IIIb or exon 9 ...
  • Signal Transduction, organism-specific biosystem (from REACTOME)
    Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
  • Signaling by FGFR, organism-specific biosystem (from REACTOME)
    Signaling by FGFR, organism-specific biosystemThe 22 members of the fibroblast growth factor (FGF) family of growth factors mediate their cellular responses by binding to and activating the different isoforms encoded by the four receptor tyrosin...
  • Signaling by FGFR2, organism-specific biosystem (from REACTOME)
    Signaling by FGFR2, organism-specific biosystemThe 22 members of the fibroblast growth factor (FGF) family of growth factors mediate their cellular responses by binding to and activating the different isoforms encoded by the four receptor tyrosin...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
AU-rich element binding IEA
Inferred from Electronic Annotation
more info
 
RNA binding HDA PubMed 
poly(A) binding TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
fibroblast growth factor receptor signaling pathway TAS
Traceable Author Statement
more info
 
negative regulation of cytokine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of translation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of epithelial cell apoptotic process IEA
Inferred from Electronic Annotation
more info
 
protein localization to cytoplasmic stress granule IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mRNA splicing, via spliceosome IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic stress granule ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol IDA
Inferred from Direct Assay
more info
 
nuclear stress granule IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
nucleolysin TIA-1 isoform p40; nucleolysin TIA-1
Names
T-cell-restricted intracellular antigen-1
p40-TIA-1 (containing p15-TIA-1)

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029967.1 RefSeqGene

    Range
    4855..44204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001351508.1NP_001338437.1  nucleolysin TIA-1 isoform p40 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Consensus CDS
    CCDS86847.1
    Related
    ENSP00000282574.4, ENST00000282574.8
    Conserved Domains (3) summary
    cd12618
    Location:105184
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:214287
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily
  2. NM_001351509.1NP_001338438.1  nucleolysin TIA-1 isoform p40 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (3) summary
    cd12618
    Location:96175
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:205278
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:883
    RRM_SF; RNA recognition motif (RRM) superfamily
  3. NM_001351510.1NP_001338439.1  nucleolysin TIA-1 isoform p40 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (3) summary
    cd12618
    Location:94173
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:203276
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily
  4. NM_001351511.1NP_001338440.1  nucleolysin TIA-1 isoform p40 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (3) summary
    cd12618
    Location:68147
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:177250
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl25887
    Location:11342
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  5. NM_001351512.1NP_001338441.1  nucleolysin TIA-1 isoform p40 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (3) summary
    cd12618
    Location:59138
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:168241
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl25887
    Location:13333
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  6. NM_001351513.1NP_001338442.1  nucleolysin TIA-1 isoform p40 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (3) summary
    cd12618
    Location:57136
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:166239
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl25887
    Location:11331
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  7. NM_001351514.1NP_001338443.1  nucleolysin TIA-1 isoform p40 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (3) summary
    cd12618
    Location:29108
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:138211
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:123
    RRM_SF; RNA recognition motif (RRM) superfamily
  8. NM_001351515.1NP_001338444.1  nucleolysin TIA-1 isoform p40 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (2) summary
    cd12618
    Location:483
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:113186
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
  9. NM_001351516.1NP_001338445.1  nucleolysin TIA-1 isoform p40 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Related
    ENSP00000399567.1, ENST00000445587.5
    Conserved Domains (2) summary
    cd12618
    Location:105184
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily
  10. NM_001351517.1NP_001338446.1  nucleolysin TIA-1 isoform p40 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4238
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  11. NM_001351518.1NP_001338447.1  nucleolysin TIA-1 isoform p40 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC016700, BC015944
    Consensus CDS
    CCDS86846.1
    Related
    ENSP00000413751.2, ENST00000416149.6
    Conserved Domains (2) summary
    cd12618
    Location:105184
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily
  12. NM_001351519.1NP_001338448.1  nucleolysin TIA-1 isoform p40 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (1) summary
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily
  13. NM_001351520.1NP_001338449.1  nucleolysin TIA-1 isoform p40 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Related
    ENSP00000427794.1, ENST00000477044.6
    Conserved Domains (1) summary
    cl17169
    Location:883
    RRM_SF; RNA recognition motif (RRM) superfamily
  14. NM_001351521.1NP_001338450.1  nucleolysin TIA-1 isoform p40 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Related
    ENSP00000354838.4, ENST00000361692.4
    Conserved Domains (1) summary
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily
  15. NM_001351522.1NP_001338451.1  nucleolysin TIA-1 isoform p40 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Consensus CDS
    CCDS86848.1
    Related
    ENSP00000430969.1, ENST00000474809.6
    Conserved Domains (1) summary
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily
  16. NM_001351523.1NP_001338452.1  nucleolysin TIA-1 isoform p40 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC016700
    Conserved Domains (1) summary
    cl17169
    Location:2982
    RRM_SF; RNA recognition motif (RRM) superfamily
  17. NM_001351524.1NP_001338453.1  nucleolysin TIA-1 isoform p40 isoform 19

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variant 20, encodes isoform 19.
    Source sequence(s)
    AC016700
    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  18. NM_001351525.1NP_001338454.1  nucleolysin TIA-1 isoform p40 isoform 19

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variant 19, encodes isoform 19.
    Source sequence(s)
    AC016700
    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  19. NM_022037.3NP_071320.2  nucleolysin TIA-1 isoform p40 isoform 1

    See identical proteins and their annotated locations for NP_071320.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) is missing exon 5, which is included in transcript variant 2, resulting in the shorter isoform (1).
    Source sequence(s)
    AC016700
    Consensus CDS
    CCDS1900.1
    UniProtKB/Swiss-Prot
    P31483
    Related
    ENSP00000404023.2, OTTHUMP00000160047, ENST00000415783.6
    Conserved Domains (3) summary
    cd12618
    Location:94173
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:203276
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily
  20. NM_022173.3NP_071505.2  nucleolysin TIA-1 isoform p40 isoform 2

    See identical proteins and their annotated locations for NP_071505.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) includes exon 5, which is missing in transcript variant 1, resulting in the longer isoform (2).
    Source sequence(s)
    AC016700
    Consensus CDS
    CCDS1901.1
    UniProtKB/Swiss-Prot
    P31483
    Related
    ENSP00000401371.2, OTTHUMP00000160046, ENST00000433529.6
    Conserved Domains (3) summary
    cd12618
    Location:105184
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:214287
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:881
    RRM_SF; RNA recognition motif (RRM) superfamily

RNA

  1. NR_147216.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  2. NR_147217.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  3. NR_147218.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  4. NR_147219.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  5. NR_147220.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  6. NR_147221.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  7. NR_147222.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  8. NR_147223.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  9. NR_147224.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  10. NR_147225.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  11. NR_147226.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  12. NR_147227.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  13. NR_147228.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  14. NR_147229.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  15. NR_147230.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  16. NR_147231.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700
  17. NR_147232.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC016700

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p12 Primary Assembly

    Range
    70209444..70248793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017004795.1XP_016860284.1  nucleolysin TIA-1 isoform X3

    Conserved Domains (2) summary
    cd12618
    Location:483
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:113186
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
  2. XM_024453067.1XP_024308835.1  nucleolysin TIA-1 isoform X5

    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4238
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  3. XM_024453064.1XP_024308832.1  nucleolysin TIA-1 isoform X4

    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  4. XM_017004794.1XP_016860283.1  nucleolysin TIA-1 isoform X2

    Conserved Domains (2) summary
    cd12621
    Location:114187
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:3484
    RRM_SF; RNA recognition motif (RRM) superfamily
  5. XM_017004800.1XP_016860289.1  nucleolysin TIA-1 isoform X4

    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  6. XM_011533082.2XP_011531384.1  nucleolysin TIA-1 isoform X2

    See identical proteins and their annotated locations for XP_011531384.1

    Conserved Domains (2) summary
    cd12621
    Location:114187
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:3484
    RRM_SF; RNA recognition motif (RRM) superfamily
  7. XM_024453066.1XP_024308834.1  nucleolysin TIA-1 isoform X4

    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  8. XM_024453063.1XP_024308831.1  nucleolysin TIA-1 isoform X4

    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  9. XM_017004792.1XP_016860281.1  nucleolysin TIA-1 isoform X2

    Conserved Domains (2) summary
    cd12621
    Location:114187
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:3484
    RRM_SF; RNA recognition motif (RRM) superfamily
  10. XM_017004796.1XP_016860285.1  nucleolysin TIA-1 isoform X4

    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  11. XM_005264531.2XP_005264588.1  nucleolysin TIA-1 isoform X3

    Conserved Domains (2) summary
    cd12618
    Location:483
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:113186
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
  12. XM_017004793.2XP_016860282.1  nucleolysin TIA-1 isoform X2

    Conserved Domains (2) summary
    cd12621
    Location:114187
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:3484
    RRM_SF; RNA recognition motif (RRM) superfamily
  13. XM_024453065.1XP_024308833.1  nucleolysin TIA-1 isoform X4

    Conserved Domains (2) summary
    cl17169
    Location:74147
    RRM_SF; RNA recognition motif (RRM) superfamily
    cl25887
    Location:4239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  14. XM_005264528.5XP_005264585.1  nucleolysin TIA-1 isoform X1

    See identical proteins and their annotated locations for XP_005264585.1

    Conserved Domains (3) summary
    cd12618
    Location:40119
    RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cd12621
    Location:149222
    RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
    cl17169
    Location:123
    RRM_SF; RNA recognition motif (RRM) superfamily

RNA

  1. XR_002959332.1 RNA Sequence

  2. XR_002959330.1 RNA Sequence

  3. XR_002959331.1 RNA Sequence

  4. XR_002959329.1 RNA Sequence

  5. XR_002959333.1 RNA Sequence

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