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SNCA synuclein alpha [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 706985, updated on 10-Feb-2026
Official Symbol
SNCAprovided by VGNC
Official Full Name
synuclein alphaprovided by VGNC
Primary source
VGNC:VGNC:77668
Locus tag
EGK_15919
See related
Ensembl:ENSMMUG00000012123
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See SNCA in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 5 NC_133410.1 (99046162..99157352, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (88118358..88230916, complement)

Chromosome 5 - NC_133410.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene GPRIN family member 3 Neighboring gene multimerin 1 Neighboring gene coiled-coil serine rich protein 1 Neighboring gene uncharacterized LOC144340986

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain. Yang W, et al. J Neurosci, 2015 May 27. PMID 26019347, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Overexpression of mutant alpha-synuclein causes age-dependent pathological changes in brain.
    Title: Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cuprous ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dopamine secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic vesicle endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon terminus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
alpha-synuclein
Names
Non-A beta component of AD amyloid
alpha-synuclein-like

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133410.1 Reference T2T-MMU8v2.0

    Range
    99046162..99157352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015138786.3 → XP_014994272.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Related
    ENSMMUP00000068039.1
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  2. XM_015138791.3 → XP_014994277.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Related
    ENSMMUP00000060035.2
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  3. XM_028848624.2 → XP_028704457.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  4. XM_028848623.2 → XP_028704456.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  5. XM_015138789.3 → XP_014994275.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  6. XM_015138784.3 → XP_014994270.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  7. XM_015138785.3 → XP_014994271.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Related
    ENSMMUP00000073855.1
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  8. XM_015138783.3 → XP_014994269.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Related
    ENSMMUP00000050306.1
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  9. XM_015138790.3 → XP_014994276.1  alpha-synuclein

    UniProtKB/Swiss-Prot
    P61143
    UniProtKB/TrEMBL
    A0A5F8A5W4, A0A8J8Y4A0, G7MTE2, H9ERB9
    Related
    ENSMMUP00000015893.3
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P61143.1 GenPept UniProtKB/Swiss-Prot:P61143

Gene LinkOut

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