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Naa30 N(alpha)-acetyltransferase 30, NatC catalytic subunit [ Mus musculus (house mouse) ]

Gene ID: 70646, updated on 26-Sep-2022

Summary

Official Symbol
Naa30provided by MGI
Official Full Name
N(alpha)-acetyltransferase 30, NatC catalytic subunitprovided by MGI
Primary source
MGI:MGI:1922259
See related
Ensembl:ENSMUSG00000036282 AllianceGenome:MGI:1922259
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nat12; 4930487N19Rik; 5730533P17Rik
Summary
Predicted to enable peptide alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal peptidyl-methionine acetylation. Predicted to be located in cytosol and nucleus. Predicted to be part of NatC complex and polysome. Orthologous to human NAA30 (N-alpha-acetyltransferase 30, NatC catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 8.0), whole brain E14.5 (RPKM 7.5) and 28 other tissues See more
Orthologs
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Genomic context

See Naa30 in Genome Data Viewer
Location:
14; 14 C1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (49409703..49428346)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (49172246..49190889)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm1570 Neighboring gene ribosomal protein L19, pseudogene 3 Neighboring gene coiled-coil domain containing 198 Neighboring gene solute carrier family 35, member F4 Neighboring gene predicted gene, 52146

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptide alpha-N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptide alpha-N-acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in N-terminal peptidyl-methionine acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in N-terminal peptidyl-methionine acetylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of NatC complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of NatC complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of polysome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
N-alpha-acetyltransferase 30
Names
N-acetyltransferase 12
N-acetyltransferase MAK3 homolog
Nalpha acetyltransferase 30
natC catalytic subunit
NP_081768.2
XP_006519605.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027492.2NP_081768.2  N-alpha-acetyltransferase 30

    Status: VALIDATED

    Source sequence(s)
    AC154227, AK015640, BC158065
    Consensus CDS
    CCDS84137.1
    UniProtKB/Swiss-Prot
    Q7TN07, Q8CES0
    Related
    ENSMUSP00000121679.2, ENSMUST00000153488.9
    Conserved Domains (2) summary
    COG0456
    Location:211364
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
    pfam00583
    Location:283341
    Acetyltransf_1; Acetyltransferase (GNAT) family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    49409703..49428346
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519542.5XP_006519605.1  N-alpha-acetyltransferase 30 isoform X1

    Related
    ENSMUSP00000041450.6, ENSMUST00000037362.6
    Conserved Domains (1) summary
    COG0456
    Location:222375
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001081430.1: Suppressed sequence

    Description
    NM_001081430.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.