CA12 carbonic anhydrase 12 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: CA12provided by VGNC
Official Full Name: carbonic anhydrase 12provided by VGNC
Primary source: VGNC:VGNC:70488
Locus tag: EGK_17571
See related: Ensembl:ENSMMUG00000021338
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2025_08	current	T2T-MMU8v2.0 (GCF_049350105.2)	7	NC_133412.1 (40654622..40714444, complement)
103	previous assembly	Mmul_10 (GCF_003339765.1)	7	NC_041760.1 (39765275..39825655, complement)

Chromosome 7 - NC_133412.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables carbonate dehydratase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: carbonic anhydrase 12

NP_001244753.1

EC 4.2.1.1

XP_014997838.1

EC 4.2.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001257824.1 → NP_001244753.1 carbonic anhydrase 12 precursor

See identical proteins and their annotated locations for NP_001244753.1

Status: PROVISIONAL

Source sequence(s)

JU336298

UniProtKB/TrEMBL

A0A1D5QX25, A0A5F8A7Y0, H9FZJ2

Related

ENSMMUP00000052605.2, ENSMMUT00000071555.2

Conserved Domains (1) summary

cd03126
Location:39 → 289

alpha_CA_XII_XIV; Carbonic anhydrase alpha, isozymes XII and XIV. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, ...

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

NC_133412.1 Reference T2T-MMU8v2.0

Range

40654622..40714444 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015142352.3 → XP_014997838.1 carbonic anhydrase 12 isoform X1

UniProtKB/TrEMBL

A0A5F7ZSY4, A0A5F8A7Y0, A0A8J8XEQ8, F7DLJ4

Related

ENSMMUP00000067749.1

Conserved Domains (1) summary

cd03126
Location:39 → 289

alpha_CA_XII_XIV; Carbonic anhydrase alpha, isozymes XII and XIV. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, ...