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Slc35d2 solute carrier family 35, member D2 [ Mus musculus (house mouse) ]

Gene ID: 70484, updated on 27-Nov-2024

Summary

Official Symbol
Slc35d2provided by MGI
Official Full Name
solute carrier family 35, member D2provided by MGI
Primary source
MGI:MGI:1917734
See related
Ensembl:ENSMUSG00000033114 AllianceGenome:MGI:1917734
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
hfrc; SQV7L; UGTrel8; mUGTrel8; 5730408I21Rik
Summary
Predicted to enable antiporter activity and pyrimidine nucleotide-sugar transmembrane transporter activity. Predicted to be involved in nucleotide-sugar transmembrane transport. Predicted to act upstream of with a positive effect on heparan sulfate proteoglycan biosynthetic process. Predicted to be active in Golgi membrane. Orthologous to human SLC35D2 (solute carrier family 35 member D2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in liver adult (RPKM 6.4), bladder adult (RPKM 3.9) and 21 other tissues See more
Orthologs
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Genomic context

See Slc35d2 in Genome Data Viewer
Location:
13 B3; 13 33.26 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (64244122..64277195, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (64096308..64129381, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30999 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 3 Neighboring gene zinc finger protein 367 Neighboring gene STARR-seq mESC enhancer starr_34820 Neighboring gene STARR-positive B cell enhancer ABC_E5404 Neighboring gene STARR-positive B cell enhancer ABC_E928 Neighboring gene STARR-positive B cell enhancer ABC_E7250 Neighboring gene hyaluronic acid binding protein 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC130109, MGC130110

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables UDP-N-acetylgalactosamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables UDP-N-acetylglucosamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables UDP-N-acetylglucosamine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables UDP-glucose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables UDP-glucuronic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide-sugar transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables nucleotide-sugar transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
nucleotide sugar transporter SLC35D2
Names
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter
UDP-galactose transporter-related protein 8
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001321.3NP_001001321.2  nucleotide sugar transporter SLC35D2

    See identical proteins and their annotated locations for NP_001001321.2

    Status: PROVISIONAL

    Source sequence(s)
    AK159148
    Consensus CDS
    CCDS26595.1
    UniProtKB/Swiss-Prot
    Q3TXR0, Q762D4, Q762D5, Q811G6
    UniProtKB/TrEMBL
    A0A0R4J181
    Related
    ENSMUSP00000097040.5, ENSMUST00000099441.6
    Conserved Domains (1) summary
    pfam03151
    Location:16301
    TPT; Triose-phosphate Transporter family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    64244122..64277195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517373.4XP_006517436.1  nucleotide sugar transporter SLC35D2 isoform X3

    UniProtKB/Swiss-Prot
    Q3TXR0, Q762D4, Q762D5, Q811G6
    Conserved Domains (1) summary
    cl26744
    Location:55238
    TPT; Triose-phosphate Transporter family
  2. XM_006517372.4XP_006517435.1  nucleotide sugar transporter SLC35D2 isoform X1

    UniProtKB/Swiss-Prot
    Q3TXR0, Q762D4, Q762D5, Q811G6
    UniProtKB/TrEMBL
    A0A1Y7VL74
    Related
    ENSMUSP00000152341.2, ENSMUST00000220792.2
    Conserved Domains (1) summary
    cl26744
    Location:16228
    TPT; Triose-phosphate Transporter family
  3. XM_006517374.4XP_006517437.1  nucleotide sugar transporter SLC35D2 isoform X4

    Conserved Domains (1) summary
    cl26744
    Location:12195
    TPT; Triose-phosphate Transporter family
  4. XM_036158165.1XP_036014058.1  nucleotide sugar transporter SLC35D2 isoform X4

    Conserved Domains (1) summary
    cl26744
    Location:12195
    TPT; Triose-phosphate Transporter family
  5. XM_036158164.1XP_036014057.1  nucleotide sugar transporter SLC35D2 isoform X2

    UniProtKB/Swiss-Prot
    Q3TXR0, Q762D4, Q762D5, Q811G6
    Conserved Domains (1) summary
    cl26744
    Location:2249
    TPT; Triose-phosphate Transporter family