Format

Send to:

Choose Destination

GABRA2 gamma-aminobutyric acid type A receptor alpha2 subunit [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 703894, updated on 6-Sep-2017

Summary

Gene symbol
GABRA2
Gene description
gamma-aminobutyric acid type A receptor alpha2 subunit
Locus tag
EGK_15690
See related
Ensembl:ENSMMUG00000003614
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs

Genomic context

See GABRA2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
11
Annotation release Status Assembly Chr Location
102 current Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (46176516..46330035, complement)
Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 5 NC_007862.1 (41431555..41577695, complement)

Chromosome 5 - NC_027897.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein SA-like Neighboring gene uncharacterized LOC106998324 Neighboring gene gamma-aminobutyric acid type A receptor gamma1 subunit Neighboring gene cytochrome c oxidase subunit VIIb2 Neighboring gene gamma-aminobutyric acid type A receptor alpha4 subunit

Genomic regions, transcripts, and products

Pathways from BioSystems

  • GABAergic synapse, organism-specific biosystem (from KEGG)
    GABAergic synapse, organism-specific biosystemGamma aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the mammalian central nervous system (CNS). When released in the synaptic cleft, GABA binds to three major classes o...
  • GABAergic synapse, conserved biosystem (from KEGG)
    GABAergic synapse, conserved biosystemGamma aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the mammalian central nervous system (CNS). When released in the synaptic cleft, GABA binds to three major classes o...
  • Morphine addiction, organism-specific biosystem (from KEGG)
    Morphine addiction, organism-specific biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
  • Morphine addiction, conserved biosystem (from KEGG)
    Morphine addiction, conserved biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
  • Neuroactive ligand-receptor interaction, organism-specific biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, organism-specific biosystem
    Neuroactive ligand-receptor interaction
  • Neuroactive ligand-receptor interaction, conserved biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, conserved biosystem
    Neuroactive ligand-receptor interaction
  • Nicotine addiction, organism-specific biosystem (from KEGG)
    Nicotine addiction, organism-specific biosystemNicotine is one of the main psychoactive ingredients in tobacco that contributes to the harmful tobacco smoking habit. A common feature of addictive drugs, including nicotine, is that they increase d...
  • Nicotine addiction, conserved biosystem (from KEGG)
    Nicotine addiction, conserved biosystemNicotine is one of the main psychoactive ingredients in tobacco that contributes to the harmful tobacco smoking habit. A common feature of addictive drugs, including nicotine, is that they increase d...
  • Retrograde endocannabinoid signaling, organism-specific biosystem (from KEGG)
    Retrograde endocannabinoid signaling, organism-specific biosystemEndogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. The family of endocannabinoids includes at least five derivatives of arachidonic...
  • Retrograde endocannabinoid signaling, conserved biosystem (from KEGG)
    Retrograde endocannabinoid signaling, conserved biosystemEndogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. The family of endocannabinoids includes at least five derivatives of arachidonic...
  • Taste transduction, organism-specific biosystem (from KEGG)
    Taste transduction, organism-specific biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...
  • Taste transduction, conserved biosystem (from KEGG)
    Taste transduction, conserved biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...

General gene information

Markers

Homology

General protein information

Preferred Names
gamma-aminobutyric acid receptor subunit alpha-2
Names
GABA(A) receptor subunit alpha-2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261668.1NP_001248597.1  gamma-aminobutyric acid receptor subunit alpha-2 precursor

    See identical proteins and their annotated locations for NP_001248597.1

    Status: PROVISIONAL

    Source sequence(s)
    JU333817
    UniProtKB/TrEMBL
    G7MSU6
    Related
    ENSMMUP00000035293.2, ENSMMUT00000042291.2
    Conserved Domains (1) summary
    cl27321
    Location:25440
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_8.0.1 Primary Assembly

Genomic

  1. NC_027897.1 Reference Mmul_8.0.1 Primary Assembly

    Range
    46176516..46330035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015138315.1XP_014993801.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X1

    Conserved Domains (2) summary
    pfam02931
    Location:16195
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:202382
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
  2. XM_015138316.1XP_014993802.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    G7MSU6
    Conserved Domains (1) summary
    cl27321
    Location:25440
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
  3. XM_015138317.1XP_014993803.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X3

    Conserved Domains (2) summary
    pfam02931
    Location:43250
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:257357
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
Support Center