CTSD cathepsin D [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: CTSD
Gene description: cathepsin D
See related: Ensembl:ENSMMUG00000003874
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: all
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Genomic context

Location:: chromosome: 14

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2025_08	current	T2T-MMU8v2.0 (GCF_049350105.2)	14	NC_133419.1 (1673575..1685767, complement)
103	previous assembly	Mmul_10 (GCF_003339765.1)	14	NC_041767.1 (1831927..1867517, complement)
103	previous assembly	Mmul_10 (GCF_003339765.1)	20	NC_041773.1 (15285166..15296969)

Chromosome 14 - NC_133419.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

D16S3302 (e-PCR)
- UniSTS:59154

stSG548468 (e-PCR)
- UniSTS:461591

stSG548469 (e-PCR)
- UniSTS:461592

MARC_10183-10184:1004371792:5 (e-PCR)
- UniSTS:267060

ECD00297 (e-PCR)
- UniSTS:281410

ECD01352 (e-PCR)
- UniSTS:282458

ECD07571 (e-PCR)
- UniSTS:288622

ECD01139 (e-PCR)
- UniSTS:282246

REN61173 (e-PCR)
- UniSTS:385973

REN61174 (e-PCR)
- UniSTS:385974

REN61179 (e-PCR)
- UniSTS:385979

REN61180 (e-PCR)
- UniSTS:385980

REN61189 (e-PCR)
- UniSTS:385989

REN61190 (e-PCR)
- UniSTS:385990

REN61193 (e-PCR)
- UniSTS:385993

REN61196 (e-PCR)
- UniSTS:385996

REN61197 (e-PCR)
- UniSTS:385997

REN61198 (e-PCR)
- UniSTS:385998

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables aspartic-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in lysosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cathepsin D

Names: cathepsin D preproprotein

XP_077816671.1

EC 3.4.23.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001438950.2 → NP_001425879.2 cathepsin D precursor

Status: VALIDATED

Source sequence(s)

JBMGST020000014

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

NC_133419.1 Reference T2T-MMU8v2.0

Range

1673575..1685767 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_077960545.1 → XP_077816671.1 cathepsin D isoform X1

UniProtKB/TrEMBL

A0A5F8AGH6

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001260554.1: Suppressed sequence

Description

NM_001260554.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.