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DUSP1 dual specificity phosphatase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 702981, updated on 8-Apr-2017

Summary

Gene symbol
DUSP1
Gene description
dual specificity phosphatase 1
Locus tag
EGK_17135
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs

Genomic context

See DUSP1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
102 current Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (171049095..171052132, complement)
Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 6 NC_007863.1 (169160191..169163252, complement)

Chromosome 6 - NC_027898.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999040 Neighboring gene neuralized E3 ubiquitin protein ligase 1B Neighboring gene uncharacterized LOC100423077 Neighboring gene endoplasmic reticulum-golgi intermediate compartment 1

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Fluid shear stress and atherosclerosis, organism-specific biosystem (from KEGG)
    Fluid shear stress and atherosclerosis, organism-specific biosystemShear stress represents the frictional force that the flow of blood exerts at the endothelial surface of the vessel wall and plays a central role in vascular biology and contributes to the progress o...
  • Fluid shear stress and atherosclerosis, conserved biosystem (from KEGG)
    Fluid shear stress and atherosclerosis, conserved biosystemShear stress represents the frictional force that the flow of blood exerts at the endothelial surface of the vessel wall and plays a central role in vascular biology and contributes to the progress o...
  • MAPK signaling pathway, organism-specific biosystem (from KEGG)
    MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
  • MAPK signaling pathway, conserved biosystem (from KEGG)
    MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
  • Serotonergic synapse, organism-specific biosystem (from KEGG)
    Serotonergic synapse, organism-specific biosystemSerotonin (5-Hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that plays important roles in physiological functions such as learning and memory, emotion, sleep, pain, motor function and endoc...

General gene information

Markers

Homology

General protein information

Preferred Names
dual specificity protein phosphatase 1
NP_001244379.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257450.2NP_001244379.1  dual specificity protein phosphatase 1

    See identical proteins and their annotated locations for NP_001244379.1

    Status: PROVISIONAL

    Source sequence(s)
    JU321828
    UniProtKB/TrEMBL
    F7ES52
    Conserved Domains (3) summary
    COG2453
    Location:188313
    CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]
    cd00127
    Location:173309
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
    cd01446
    Location:7136
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_8.0.1 Primary Assembly

Genomic

  1. NC_027898.1 Reference Mmul_8.0.1 Primary Assembly

    Range
    171049095..171052132 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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