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MYLIP myosin regulatory light chain interacting protein [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 702625, updated on 14-Dec-2025
Official Symbol
MYLIPprovided by VGNC
Official Full Name
myosin regulatory light chain interacting proteinprovided by VGNC
Primary source
VGNC:VGNC:75000
See related
Ensembl:ENSMMUG00000057657
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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See MYLIP in Genome Data Viewer
Location:
chromosome: 4
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 4 NC_133409.1 (166966674..166985772, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (153851637..153870757, complement)

Chromosome 4 - NC_133409.1Genomic Context describing neighboring genes Neighboring gene p53 apoptosis effector related to PMP-22 pseudogene Neighboring gene small nucleolar RNA U3 Neighboring gene malate dehydrogenase, cytoplasmic pseudogene Neighboring gene 5S ribosomal RNA

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytoskeletal protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin-protein ligase MYLIP
NP_001248724.1
XP_014991041.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261795.2 → NP_001248724.1  E3 ubiquitin-protein ligase MYLIP

    See identical proteins and their annotated locations for NP_001248724.1

    Status: PROVISIONAL

    Source sequence(s)
    JV045677
    UniProtKB/TrEMBL
    F6QA16, G7MQS4, H9ES76
    Related
    ENSMMUP00000065793.1, ENSMMUT00000083192.1
    Conserved Domains (5) summary
    smart00295
    Location:5 → 190
    B41; Band 4.1 homologues
    cd13195
    Location:185 → 295
    FERM_C_MYLIP_IDOL; FERM domain C-lobe of E3 ubiquitin ligase myosin regulatory light chain-interacting protein (MYLIP; also called inducible degrader of the LDL receptor, IDOL)
    pfam00373
    Location:85 → 190
    FERM_M; FERM central domain
    pfam09379
    Location:5 → 67
    FERM_N; FERM N-terminal domain
    pfam13920
    Location:383 → 428
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133409.1 Reference T2T-MMU8v2.0

    Range
    166966674..166985772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015135555.3 → XP_014991041.1  E3 ubiquitin-protein ligase MYLIP isoform X1

    UniProtKB/TrEMBL
    G7MQS4
    Conserved Domains (5) summary
    smart00295
    Location:5 → 135
    B41; Band 4.1 homologues
    pfam00373
    Location:85 → 140
    FERM_M; FERM central domain
    pfam09379
    Location:5 → 67
    FERM_N; FERM N-terminal domain
    pfam13920
    Location:317 → 362
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    cl17171
    Location:154 → 229
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials