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WLS Wnt ligand secretion mediator [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701411, updated on 10-Feb-2026
Official Symbol
WLSprovided by VGNC
Official Full Name
Wnt ligand secretion mediatorprovided by VGNC
Primary source
VGNC:VGNC:79839
See related
Ensembl:ENSMMUG00000022908
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
GPR177
Orthologs
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Try the new Transcripts and proteins table
See WLS in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 1 NC_133406.1 (172369811..172505766)
103 previous assembly Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (156188013..156323672)

Chromosome 1 - NC_133406.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114672101 Neighboring gene uncharacterized LOC144338508 Neighboring gene C-terminal-binding protein 2 pseudogene Neighboring gene microRNA mir-1262 Neighboring gene uncharacterized LOC106999161 Neighboring gene DIRAS family GTPase 3 Neighboring gene G protein subunit gamma 12 Neighboring gene U7 small nuclear RNA

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Wnt protein secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in organelle membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
protein wntless homolog
Names
wntless Wnt ligand secretion mediator
wntless homolog

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133406.1 Reference T2T-MMU8v2.0

    Range
    172369811..172505766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028832614.2XP_028688447.1  protein wntless homolog isoform X3

    UniProtKB/TrEMBL
    A0A5K1UTP1
    Conserved Domains (1) summary
    pfam06664
    Location:115433
    MIG-14_Wnt-bd; Wnt-binding factor required for Wnt secretion
  2. XM_077988404.1XP_077844530.1  protein wntless homolog isoform X4

    UniProtKB/TrEMBL
    F6W7D4
  3. XM_015142045.3XP_014997531.1  protein wntless homolog isoform X1

    UniProtKB/TrEMBL
    A0A5K1UTP1, H9G004
    Related
    ENSMMUP00000046164.2
    Conserved Domains (1) summary
    pfam06664
    Location:178496
    MIG-14_Wnt-bd; Wnt-binding factor required for Wnt secretion
  4. XM_015142050.3XP_014997536.1  protein wntless homolog isoform X2

    UniProtKB/TrEMBL
    F6W7D4, H9G005
    Related
    ENSMMUP00000076586.1
    Conserved Domains (1) summary
    pfam06664
    Location:178496
    MIG-14_Wnt-bd; Wnt-binding factor required for Wnt secretion