SH3BP1 SH3 domain binding protein 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: SH3BP1
Gene description: SH3 domain binding protein 1
See related: Ensembl:ENSMMUG00000003854
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2025_08	current	T2T-MMU8v2.0 (GCF_049350105.2)	10	NC_133415.1 (13879261..13895387, complement)
103	previous assembly	Mmul_10 (GCF_003339765.1)	10	NC_041763.1 (13891259..13919414, complement)

Chromosome 10 - NC_133415.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of Rac protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in intracellular anatomical structure	IEA Inferred from Electronic Annotation more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_015150292.3 → XP_015005778.1 SH3 domain-binding protein 1 isoform X1

UniProtKB/TrEMBL

F7HAB0

Related

ENSMMUP00000005139.4

Conserved Domains (2) summary

cl02570
Location:272 → 473

RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

cl12013
Location:16 → 272

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_077949685.1 → XP_077805811.1 SH3 domain-binding protein 1 isoform X3

UniProtKB/TrEMBL

F6QUV4
XM_077949684.1 → XP_077805810.1 SH3 domain-binding protein 1 isoform X2