GEN1 GEN1 Holliday junction 5' flap endonuclease [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: GEN1provided by VGNC
Official Full Name: GEN1 Holliday junction 5' flap endonucleaseprovided by VGNC
Primary source: VGNC:VGNC:72790
See related: Ensembl:ENSMMUG00000012058
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: all
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Try the new Transcripts and proteins table

Annotation release	Status	Assembly	Chr	Location
RS_2025_08	current	T2T-MMU8v2.0 (GCF_049350105.2)	13	NC_133418.1 (107227077..107261140, complement)
103	previous assembly	Mmul_10 (GCF_003339765.1)	13	NC_041766.1 (91183452..91215511, complement)

Chromosome 13 - NC_133418.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables 5'-flap endonuclease activity	IEA Inferred from Electronic Annotation more info	PubMed
enables four-way junction DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_015111758.3 → XP_014967244.1 flap endonuclease GEN homolog 1

UniProtKB/TrEMBL

F7HFT8, G7N9F8, H9Z8I9

Related

ENSMMUP00000015816.2

Conserved Domains (2) summary

cd09905
Location:195 → 338

H3TH_GEN1; H3TH domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease

cd09869
Location:2 → 206

PIN_GEN1; FEN-like PIN domains of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
XM_077958719.1 → XP_077814845.1 flap endonuclease GEN homolog 1

UniProtKB/TrEMBL

F7HFT8, G7N9F8, H9Z8I9