U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Polr2i polymerase (RNA) II (DNA directed) polypeptide I [ Mus musculus (house mouse) ]

Gene ID: 69920, updated on 26-Sep-2022

Summary

Official Symbol
Polr2iprovided by MGI
Official Full Name
polymerase (RNA) II (DNA directed) polypeptide Iprovided by MGI
Primary source
MGI:MGI:1917170
See related
Ensembl:ENSMUSG00000019738 AllianceGenome:MGI:1917170
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810002B19Rik
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; and transcription-coupled nucleotide-excision repair. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II, core complex. Is expressed in several structures, including alimentary system; blastocyst; integumental system; nervous system; and urinary system. Orthologous to human POLR2I (RNA polymerase II subunit I). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 84.8), whole brain E14.5 (RPKM 58.9) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Polr2i in Genome Data Viewer
Location:
7; 7 B1
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29931499..29932812)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30232074..30233387)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53356 Neighboring gene cytochrome c oxidase subunit 7A1 Neighboring gene calpain, small subunit 1 Neighboring gene tubulin folding cofactor B Neighboring gene ovo like zinc finger 3 Neighboring gene WD repeat domain 62 Neighboring gene ribosomal protein S12, pseudogene 5 Neighboring gene RIKEN cDNA 1700020L13 gene Neighboring gene THAP domain containing 8, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC73656

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to DNA-directed 5'-3' RNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
 
part_of RNA polymerase II, core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of RNA polymerase II, core complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
DNA-directed RNA polymerase II subunit RPB9
Names
DNA-directed RNA polymerase II subunit I
RNA polymerase II 14.5 kDa subunit
RNA polymerase II subunit B9
RPB14.5
NP_081535.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027259.1NP_081535.1  DNA-directed RNA polymerase II subunit RPB9

    See identical proteins and their annotated locations for NP_081535.1

    Status: PROVISIONAL

    Source sequence(s)
    BC062812
    Consensus CDS
    CCDS21084.1
    UniProtKB/Swiss-Prot
    P60898
    UniProtKB/TrEMBL
    A0A6P5PUH6
    Related
    ENSMUSP00000019882.10, ENSMUST00000019882.16
    Conserved Domains (2) summary
    COG1594
    Location:14125
    RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]
    cd10508
    Location:74124
    Zn-ribbon_RPB9; C-terminal zinc ribbon domain of RPB9 subunit of RNA polymerase II

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    29931499..29932812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)