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Rab3b RAB3B, member RAS oncogene family [ Mus musculus (house mouse) ]

Gene ID: 69908, updated on 23-Nov-2021

Summary

Official Symbol
Rab3bprovided by MGI
Official Full Name
RAB3B, member RAS oncogene familyprovided by MGI
Primary source
MGI:MGI:1917158
See related
Ensembl:ENSMUSG00000003411
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610528C18Rik
Expression
Biased expression in CNS E18 (RPKM 19.6), frontal lobe adult (RPKM 19.1) and 14 other tissues See more
Orthologs
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Genomic context

See Rab3b in Genome Data Viewer
Location:
4; 4 C7
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (108736267..108800521)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (108879070..108943324)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (108551675..108615929)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene basic transcription factor 3-like 4 Neighboring gene thioredoxin domain containing 12 (endoplasmic reticulum) Neighboring gene KTI12 homolog, chromatin associated Neighboring gene RIKEN cDNA 8030443G20 gene Neighboring gene nardilysin, N-arginine dibasic convertase, NRD convertase 1 Neighboring gene microRNA 761 Neighboring gene oxysterol binding protein-like 9 Neighboring gene predicted gene, 32581

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GDP binding ISO
Inferred from Sequence Orthology
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTP-dependent protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables GTPase activity ISO
Inferred from Sequence Orthology
more info
 
enables myosin V binding ISO
Inferred from Sequence Orthology
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in anchored component of synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in dopaminergic synapse ISO
Inferred from Sequence Orthology
more info
 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with secretory granule IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in vesicle ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023537.5NP_076026.1  ras-related protein Rab-3B

    See identical proteins and their annotated locations for NP_076026.1

    Status: PROVISIONAL

    Source sequence(s)
    AL607070
    Consensus CDS
    CCDS18459.1
    UniProtKB/Swiss-Prot
    Q9CZT8
    UniProtKB/TrEMBL
    Q0PD62
    Related
    ENSMUSP00000102261.3, ENSMUST00000106650.9
    Conserved Domains (1) summary
    cd01865
    Location:22186
    Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    108736267..108800521
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164406.1XP_036020299.1  ras-related protein Rab-3B isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:191
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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