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Slc25a32 solute carrier family 25, member 32 [ Mus musculus (house mouse) ]

Gene ID: 69906, updated on 5-Mar-2024

Summary

Official Symbol
Slc25a32provided by MGI
Official Full Name
solute carrier family 25, member 32provided by MGI
Primary source
MGI:MGI:1917156
See related
Ensembl:ENSMUSG00000022299 AllianceGenome:MGI:1917156
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mftc; 2610043O12Rik
Summary
Predicted to enable FAD transmembrane transporter activity and folic acid transmembrane transporter activity. Involved in folate import into mitochondrion. Located in mitochondrion. Is expressed in embryo and metencephalon floor plate. Orthologous to human SLC25A32 (solute carrier family 25 member 32). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 2.4), adrenal adult (RPKM 2.1) and 28 other tissues See more
Orthologs
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Genomic context

Location:
15 B3.1; 15 15.39 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (38954625..38976213, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (39091230..39112720, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene 7194 Neighboring gene STARR-seq mESC enhancer starr_38471 Neighboring gene collagen triple helix repeat containing 1 Neighboring gene STARR-seq mESC enhancer starr_38472 Neighboring gene STARR-positive B cell enhancer mm9_chr15:38944202-38944502 Neighboring gene DDB1 and CUL4 associated factor 13 Neighboring gene STARR-seq mESC enhancer starr_38473 Neighboring gene STARR-seq mESC enhancer starr_38474 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (5)  1 citation

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables FAD transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables FAD transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables FAD transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables folic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables folic acid transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in folate import into mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in folate import into mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in folate import into mitochondrion ISO
Inferred from Sequence Orthology
more info
 
involved_in mitochondrial FAD transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitochondrial FAD transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in nucleotide transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier family 25 member 32
Names
mitochondrial FAD transporter
mitochondrial folate transporter/carrier

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172402.3NP_765990.2  solute carrier family 25 member 32

    See identical proteins and their annotated locations for NP_765990.2

    Status: VALIDATED

    Source sequence(s)
    AK145178, AK167501, BB308144, BB641480
    Consensus CDS
    CCDS27443.1
    UniProtKB/Swiss-Prot
    Q3TCM5, Q8BMG8
    UniProtKB/TrEMBL
    Q8K0B7
    Related
    ENSMUSP00000022908.9, ENSMUST00000022908.10
    Conserved Domains (2) summary
    PTZ00169
    Location:26307
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:116213
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    38954625..38976213 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159580.1XP_036015473.1  solute carrier family 25 member 32 isoform X3

    UniProtKB/TrEMBL
    Q3T9D8
    Conserved Domains (1) summary
    pfam00153
    Location:116213
    Mito_carr; Mitochondrial carrier protein
  2. XM_006521385.5XP_006521448.1  solute carrier family 25 member 32 isoform X2

    UniProtKB/TrEMBL
    Q3T9D8
    Conserved Domains (1) summary
    pfam00153
    Location:118212
    Mito_carr; Mitochondrial carrier protein
  3. XM_036159581.1XP_036015474.1  solute carrier family 25 member 32 isoform X4

    UniProtKB/TrEMBL
    Q3T9D8
    Conserved Domains (1) summary
    pfam00153
    Location:23109
    Mito_carr; Mitochondrial carrier protein
  4. XM_036159578.1XP_036015471.1  solute carrier family 25 member 32 isoform X1

    UniProtKB/TrEMBL
    Q8K0B7
    Related
    ENSMUSP00000154227.2, ENSMUST00000227323.2
    Conserved Domains (2) summary
    PTZ00169
    Location:26292
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:206294
    Mito_carr; Mitochondrial carrier protein