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MLH1 mutL homolog 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 698782, updated on 10-Feb-2026
Official Symbol
MLH1provided by VGNC
Official Full Name
mutL homolog 1provided by VGNC
Primary source
VGNC:VGNC:74880
See related
Ensembl:ENSMMUG00000022533
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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Try the new Transcripts and proteins table
See MLH1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 2 NC_133407.1 (99250374..99305016)
103 previous assembly Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (92414222..92469110)

Chromosome 2 - NC_133407.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC144339110 Neighboring gene EPM2A interacting protein 1 Neighboring gene uncharacterized LOC114676315 Neighboring gene LRR binding FLII interacting protein 2 Neighboring gene U6 spliceosomal RNA Neighboring gene ubiquitin-conjugating enzyme E2 D3 pseudogene

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques. Brammer DW, et al. Proc Natl Acad Sci U S A, 2018 Mar 13. PMID 29490919, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in somatic hypermutation of immunoglobulin genes IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MutLalpha complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
DNA mismatch repair protein Mlh1
Names
mutL homolog 1, colon cancer, nonpolyposis type 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133407.1 Reference T2T-MMU8v2.0

    Range
    99250374..99305016
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_077992066.1 → XP_077848192.1  DNA mismatch repair protein Mlh1 isoform X12

  2. XM_077992068.1 → XP_077848194.1  DNA mismatch repair protein Mlh1 isoform X12

  3. XM_077992067.1 → XP_077848193.1  DNA mismatch repair protein Mlh1 isoform X12

  4. XM_077992078.1 → XP_077848204.1  DNA mismatch repair protein Mlh1 isoform X13

  5. XM_077992083.1 → XP_077848209.1  DNA mismatch repair protein Mlh1 isoform X15

  6. XM_077992080.1 → XP_077848206.1  DNA mismatch repair protein Mlh1 isoform X14

  7. XM_077992077.1 → XP_077848203.1  DNA mismatch repair protein Mlh1 isoform X12

  8. XM_077992063.1 → XP_077848189.1  DNA mismatch repair protein Mlh1 isoform X10

    UniProtKB/TrEMBL
    H9FUL2

  9. XM_077992054.1 → XP_077848180.1  DNA mismatch repair protein Mlh1 isoform X3

    UniProtKB/TrEMBL
    H9FUL2

  10. XM_077992079.1 → XP_077848205.1  DNA mismatch repair protein Mlh1 isoform X13

  11. XM_077992071.1 → XP_077848197.1  DNA mismatch repair protein Mlh1 isoform X12

  12. XM_077992082.1 → XP_077848208.1  DNA mismatch repair protein Mlh1 isoform X15

  13. XM_015131399.3 → XP_014986885.3  DNA mismatch repair protein Mlh1 isoform X1

    UniProtKB/TrEMBL
    H9FUL2

  14. XM_015131400.3 → XP_014986886.3  DNA mismatch repair protein Mlh1 isoform X4

    UniProtKB/TrEMBL
    H9FUL2

  15. XM_077992056.1 → XP_077848182.1  DNA mismatch repair protein Mlh1 isoform X6

    UniProtKB/TrEMBL
    H9FUL2

  16. XM_077992059.1 → XP_077848185.1  DNA mismatch repair protein Mlh1 isoform X9

    UniProtKB/TrEMBL
    H9FUL2

  17. XM_077992058.1 → XP_077848184.1  DNA mismatch repair protein Mlh1 isoform X8

    UniProtKB/TrEMBL
    H9FUL2

  18. XM_028843927.2 → XP_028699760.2  DNA mismatch repair protein Mlh1 isoform X15

  19. XM_028843925.2 → XP_028699758.2  DNA mismatch repair protein Mlh1 isoform X2

    UniProtKB/TrEMBL
    H9FUL2

  20. XM_077992055.1 → XP_077848181.1  DNA mismatch repair protein Mlh1 isoform X5

    UniProtKB/TrEMBL
    H9FUL2

  21. XM_077992072.1 → XP_077848198.1  DNA mismatch repair protein Mlh1 isoform X12

  22. XM_077992073.1 → XP_077848199.1  DNA mismatch repair protein Mlh1 isoform X12

  23. XM_077992061.1 → XP_077848187.1  DNA mismatch repair protein Mlh1 isoform X10

    UniProtKB/TrEMBL
    H9FUL2

  24. XM_077992064.1 → XP_077848190.1  DNA mismatch repair protein Mlh1 isoform X11

    UniProtKB/TrEMBL
    H9FUL2

  25. XM_077992075.1 → XP_077848201.1  DNA mismatch repair protein Mlh1 isoform X12

  26. XM_077992057.1 → XP_077848183.1  DNA mismatch repair protein Mlh1 isoform X7

    UniProtKB/TrEMBL
    H9FUL2

  27. XM_028843926.2 → XP_028699759.2  DNA mismatch repair protein Mlh1 isoform X12

  28. XM_028843928.2 → XP_028699761.2  DNA mismatch repair protein Mlh1 isoform X15

  29. XM_077992074.1 → XP_077848200.1  DNA mismatch repair protein Mlh1 isoform X12

  30. XM_077992076.1 → XP_077848202.1  DNA mismatch repair protein Mlh1 isoform X12

  31. XM_077992062.1 → XP_077848188.1  DNA mismatch repair protein Mlh1 isoform X10

    UniProtKB/TrEMBL
    H9FUL2

  32. XM_077992065.1 → XP_077848191.1  DNA mismatch repair protein Mlh1 isoform X11

    UniProtKB/TrEMBL
    H9FUL2

  33. XM_077992084.1 → XP_077848210.1  DNA mismatch repair protein Mlh1 isoform X15

  34. XM_077992069.1 → XP_077848195.1  DNA mismatch repair protein Mlh1 isoform X12

Nucleotide Protein
Heading Accession and Version

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