Ndufa11 NADH:ubiquinone oxidoreductase subunit A11 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ndufa11provided by MGI
Official Full Name: NADH:ubiquinone oxidoreductase subunit A11provided by MGI
Primary source: MGI:MGI:1917125
See related: Ensembl:ENSMUSG00000002379 AllianceGenome:MGI:1917125
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: B14.7; 2010012C24Rik
Summary: Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in genitourinary system. Human ortholog(s) of this gene implicated in communication disorder and nuclear type mitochondrial complex I deficiency 14. Orthologous to human NDUFA11 (NADH:ubiquinone oxidoreductase subunit A11). [provided by Alliance of Genome Resources, Apr 2025]
Expression: Ubiquitous expression in heart adult (RPKM 87.4), duodenum adult (RPKM 80.9) and 28 other tissues See more
Orthologs: all
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Genomic context

Location:: 17 29.47 cM; 17 D

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (57024762..57031248)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (56717762..56724248)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (1) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in aerobic respiration	NAS Non-traceable Author Statement more info	PubMed
involved_in mitochondrial electron transport, NADH to ubiquinone	IEA Inferred from Electronic Annotation more info
involved_in proton motive force-driven mitochondrial ATP synthesis	NAS Non-traceable Author Statement more info	PubMed
involved_in respiratory electron transport chain	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex I	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex I	ISO Inferred from Sequence Orthology more info
part_of respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

Names: CI-B14.7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11; NADH-ubiquinone oxidoreductase subunit B14.7; complex I-B14.7

NP_081520.1

EC 7.1.1.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_027244.1 → NP_081520.1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

See identical proteins and their annotated locations for NP_081520.1

Status: VALIDATED

Source sequence(s)

CT010491

Consensus CDS

CCDS50155.1

UniProtKB/Swiss-Prot

Q9D8B4

UniProtKB/TrEMBL

G5E814

Related

ENSMUSP00000002452.7, ENSMUST00000002452.8

Conserved Domains (1) summary

pfam02466
Location:20 → 124

Tim17; Tim17/Tim22/Tim23/Pmp24 family