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GCN1 GCN1 activator of EIF2AK4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 698528, updated on 12-Dec-2025
Official Symbol
GCN1provided by VGNC
Official Full Name
GCN1 activator of EIF2AK4provided by VGNC
Primary source
VGNC:VGNC:72905
Locus tag
EGK_04253
See related
Ensembl:ENSMMUG00000009152
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
GCN1L1
Orthologs
human mouse all
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See GCN1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
58
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 11 NC_133416.1 (127423424..127491969, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (119906202..119974890, complement)

Chromosome 11 - NC_133416.1Genomic Context describing neighboring genes Neighboring gene BICD family like cargo adaptor 1 Neighboring gene uncharacterized LOC144333160 Neighboring gene uncharacterized LOC114670969 Neighboring gene RAB35, member RAS oncogene family Neighboring gene ribosomal protein lateral stalk subunit P0 Neighboring gene paxillin

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to amino acid starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
eIF-2-alpha kinase activator GCN1; stalled ribosome sensor GCN1
Names
GCN1 general control of amino-acid synthesis 1-like 1
GCN1, eIF2 alpha kinase activator homolog
translational activator GCN1

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RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133416.1 Reference T2T-MMU8v2.0

    Range
    127423424..127491969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015152949.3 → XP_015008435.1  stalled ribosome sensor GCN1 isoform X2

    UniProtKB/TrEMBL
    A0A5K1VRX8, H9FP65, I0FNS6
    Related
    ENSMMUP00000058844.1
    Conserved Domains (4) summary
    cd00020
    Location:1498 → 1601
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam12074
    Location:356 → 705
    DUF3554; Domain of unknown function (DUF3554)
    pfam13646
    Location:1616 → 1721
    HEAT_2; HEAT repeats
    sd00044
    Location:1461 → 1485
    HEAT; HEAT repeat [structural motif]

  2. XM_015152948.3 → XP_015008434.1  stalled ribosome sensor GCN1 isoform X1

    UniProtKB/TrEMBL
    H9FP65, I0FNS6
    Conserved Domains (4) summary
    cd00020
    Location:1504 → 1607
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam12074
    Location:356 → 711
    DUF3554; Domain of unknown function (DUF3554)
    pfam13646
    Location:1622 → 1727
    HEAT_2; HEAT repeats
    sd00044
    Location:1467 → 1491
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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