Format

Send to:

Choose Destination

LRRK2 leucine rich repeat kinase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 697930, updated on 29-Apr-2017
Gene symbol
LRRK2
Gene description
leucine rich repeat kinase 2
See related
Ensembl:ENSMMUG00000015857
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
Location:
chromosome: 11
Exon count:
52
Annotation release Status Assembly Chr Location
102 current Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (37964353..38110230)
Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 11 NC_007868.1 (37105628..37248702)

Chromosome 11 - NC_027903.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 2 member 13 Neighboring gene 60S ribosomal protein L30-like Neighboring gene uncharacterized LOC107000826 Neighboring gene mucin 19, oligomeric Neighboring gene methionine aminopeptidase 1 pseudogene Neighboring gene contactin 1

  • Parkinson's disease, organism-specific biosystem (from KEGG)
    Parkinson's disease, organism-specific biosystemParkinson's disease (PD) is a progressive neurodegenerative movement disorder that results primarily from the death of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Mutations...

Markers

Homology

Preferred Names
leucine-rich repeat serine/threonine-protein kinase 2
XP_015006935.1
XP_015006936.1
XP_015006937.1

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_8.0.1 Primary Assembly

Genomic

  1. NC_027903.1 Reference Mmul_8.0.1 Primary Assembly

    Range
    37964353..38110230
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015151450.1XP_015006936.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X2

    UniProtKB/TrEMBL
    F7C7Z0
    Related
    ENSMMUP00000020845.3, ENSMMUT00000022280.3
    Conserved Domains (7) summary
    cd09914
    Location:13341507
    RocCOR; Ras of complex proteins (Roc) C-terminal of Roc (COR) domain family
    smart00220
    Location:18842128
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG1100
    Location:13331568
    Gem1; GTPase SAR1 family domain [General function prediction only]
    COG4886
    Location:11081360
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14068
    Location:18842135
    STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
    sd00033
    Location:10131036
    LRR_RI; leucine-rich repeat [structural motif]
    pfam16095
    Location:15271740
    COR; C-terminal of Roc, COR, domain
  2. XM_015151449.1XP_015006935.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X1

    Conserved Domains (7) summary
    cd09914
    Location:13341507
    RocCOR; Ras of complex proteins (Roc) C-terminal of Roc (COR) domain family
    smart00220
    Location:18842128
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG1100
    Location:13331568
    Gem1; GTPase SAR1 family domain [General function prediction only]
    COG4886
    Location:11081360
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14068
    Location:18842135
    STKc_LRRK2; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 2
    sd00033
    Location:10131036
    LRR_RI; leucine-rich repeat [structural motif]
    pfam16095
    Location:15271740
    COR; C-terminal of Roc, COR, domain
  3. XM_015151451.1XP_015006937.1  leucine-rich repeat serine/threonine-protein kinase 2 isoform X3

    Conserved Domains (7) summary
    cd09914
    Location:13341507
    RocCOR; Ras of complex proteins (Roc) C-terminal of Roc (COR) domain family
    smart00220
    Location:18842068
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG1100
    Location:13331568
    Gem1; GTPase SAR1 family domain [General function prediction only]
    COG4886
    Location:11081360
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:10131036
    LRR_RI; leucine-rich repeat [structural motif]
    pfam16095
    Location:15271740
    COR; C-terminal of Roc, COR, domain
    cl21453
    Location:18842093
    PKc_like; Protein Kinases, catalytic domain
Support Center