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Ms4a6b membrane-spanning 4-domains, subfamily A, member 6B [ Mus musculus (house mouse) ]

Gene ID: 69774, updated on 8-Mar-2025

Summary

Official Symbol
Ms4a6bprovided by MGI
Official Full Name
membrane-spanning 4-domains, subfamily A, member 6Bprovided by MGI
Primary source
MGI:MGI:1917024
See related
Ensembl:ENSMUSG00000024677 AllianceGenome:MGI:1917024
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810027D10Rik
Summary
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane and trans-Golgi network. Is expressed in genitourinary system. Orthologous to several human genes including MS4A6A (membrane spanning 4-domains A6A). [provided by Alliance of Genome Resources, Mar 2025]
Expression
Broad expression in spleen adult (RPKM 14.6), thymus adult (RPKM 14.5) and 16 other tissues See more
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Genomic context

See Ms4a6b in Genome Data Viewer
Location:
19 A; 19 8.44 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11495923..11507767)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11518559..11530403)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene membrane-spanning 4-domains, subfamily A, member 6C Neighboring gene expressed sequence BE692007 Neighboring gene STARR-positive B cell enhancer ABC_E7634 Neighboring gene STARR-positive B cell enhancer ABC_E4266 Neighboring gene STARR-positive B cell enhancer ABC_E11672 Neighboring gene STARR-positive B cell enhancer ABC_E8739 Neighboring gene predicted gene 8369 Neighboring gene membrane-spanning 4-domains, subfamily A, member 4D Neighboring gene membrane-spanning 4-domains subfamily A member 6D-like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
membrane-spanning 4-domains subfamily A member 6B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027209.3NP_081485.2  membrane-spanning 4-domains subfamily A member 6B

    See identical proteins and their annotated locations for NP_081485.2

    Status: PROVISIONAL

    Source sequence(s)
    AC165168
    Consensus CDS
    CCDS29601.1
    UniProtKB/Swiss-Prot
    Q8BK83, Q99N09, Q9D8W9
    Related
    ENSMUSP00000025580.4, ENSMUST00000025580.10
    Conserved Domains (1) summary
    pfam04103
    Location:47204
    CD20; CD20-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    11495923..11507767
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)