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GRM8 glutamate metabotropic receptor 8 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 697465, updated on 10-Feb-2026
Official Symbol
GRM8provided by VGNC
Official Full Name
glutamate metabotropic receptor 8provided by VGNC
Primary source
VGNC:VGNC:73292
See related
Ensembl:ENSMMUG00000015240
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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Try the new Transcripts and proteins table
See GRM8 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 3 NC_133408.1 (166286790..167092489, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (152900015..153709715, complement)

Chromosome 3 - NC_133408.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC144340204 Neighboring gene endogenous retrovirus group FC1 Env polyprotein-like Neighboring gene keratin 18-like Neighboring gene uncharacterized LOC144339918 Neighboring gene microRNA mir-592 Neighboring gene U2 spliceosomal RNA Neighboring gene PRELI domain containing protein 3B pseudogene

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
metabotropic glutamate receptor 8

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261246.1 → NP_001248175.1  metabotropic glutamate receptor 8

    See identical proteins and their annotated locations for NP_001248175.1

    Status: PROVISIONAL

    Source sequence(s)
    JU322197
    UniProtKB/TrEMBL
    F6VUY3, G7MM89, H9EU94
    Related
    ENSMMUP00000019977.4, ENSMMUT00000021363.4
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133408.1 Reference T2T-MMU8v2.0

    Range
    166286790..167092489 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_077994722.1 → XP_077850848.1  metabotropic glutamate receptor 8 isoform X4

    UniProtKB/TrEMBL
    G7MM89

  2. XM_077994723.1 → XP_077850849.1  metabotropic glutamate receptor 8 isoform X5

  3. XM_028844840.2 → XP_028700673.1  metabotropic glutamate receptor 8 isoform X2

    UniProtKB/TrEMBL
    G7MM89
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  4. XM_077994717.1 → XP_077850843.1  metabotropic glutamate receptor 8 isoform X1

    UniProtKB/TrEMBL
    G7MM89

  5. XM_077994721.1 → XP_077850847.1  metabotropic glutamate receptor 8 isoform X3

    UniProtKB/TrEMBL
    F6VUY3, G7MM89, H9EU94

  6. XM_077994720.1 → XP_077850846.1  metabotropic glutamate receptor 8 isoform X2

    UniProtKB/TrEMBL
    G7MM89

  7. XM_077994719.1 → XP_077850845.1  metabotropic glutamate receptor 8 isoform X2

    UniProtKB/TrEMBL
    G7MM89

  8. XM_077994718.1 → XP_077850844.1  metabotropic glutamate receptor 8 isoform X1

    UniProtKB/TrEMBL
    G7MM89

  9. XM_015134808.3 → XP_014990294.1  metabotropic glutamate receptor 8 isoform X3

    UniProtKB/TrEMBL
    F6VUY3, G7MM89, H9EU94
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor

  10. XM_077994724.1 → XP_077850850.1  metabotropic glutamate receptor 8 isoform X6

RNA

  1. XR_013414643.1 RNA Sequence

  2. XR_013414645.1 RNA Sequence

  3. XR_013414644.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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