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Ttl tubulin tyrosine ligase [ Mus musculus (house mouse) ]

Gene ID: 69737, updated on 23-Jun-2021

Summary

Official Symbol
Ttlprovided by MGI
Official Full Name
tubulin tyrosine ligaseprovided by MGI
Primary source
MGI:MGI:1916987
See related
Ensembl:ENSMUSG00000027394
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI848570; 2410003M22Rik; 2700049H19Rik
Expression
Ubiquitous expression in CNS E18 (RPKM 12.5), cortex adult (RPKM 10.7) and 27 other tissues See more
Orthologs
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Genomic context

See Ttl in Genome Data Viewer
Location:
2; 2 F1
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (128907867..128938203)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (129065947..129096283)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (128891683..128922019)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH type containing 6 Neighboring gene vinculin/alpha-catenin family member 1 Neighboring gene predicted gene, 54152 Neighboring gene predicted gene, 46764 Neighboring gene polymerase (RNA) I polypeptide B Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables tubulin-tyrosine ligase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables tubulin-tyrosine ligase activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in microtubule IC
Inferred by Curator
more info
PubMed 
located_in spindle microtubule ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
tubulin--tyrosine ligase
NP_081468.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027192.2NP_081468.1  tubulin--tyrosine ligase

    See identical proteins and their annotated locations for NP_081468.1

    Status: VALIDATED

    Source sequence(s)
    AL833780
    Consensus CDS
    CCDS16719.1
    UniProtKB/Swiss-Prot
    P38585
    Related
    ENSMUSP00000046883.8, ENSMUST00000035812.14
    Conserved Domains (1) summary
    pfam03133
    Location:81363
    TTL; Tubulin-tyrosine ligase family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    128907867..128938203
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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