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Ptrhd1 peptidyl-tRNA hydrolase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 69709, updated on 8-Apr-2026
Official Symbol
Ptrhd1provided by MGI
Official Full Name
peptidyl-tRNA hydrolase domain containing 1provided by MGI
Primary source
MGI:MGI:1916959
See related
Ensembl:ENSMUSG00000096199 AllianceGenome:MGI:1916959
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410017P09Rik
Summary
Predicted to enable peptidyl-tRNA hydrolase activity. Orthologous to human PTRHD1 (peptidyl-tRNA hydrolase domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Ubiquitous expression in kidney adult (RPKM 12.6), adrenal adult (RPKM 5.7) and 28 other tissues See more
Orthologs
all
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Try the new Transcripts and proteins table
See Ptrhd1 in Genome Data Viewer
Location:
12 A1.1; 12 2.04 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (4284013..4290123)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (4234013..4240123)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_31436 Neighboring gene adenylate cyclase 3 Neighboring gene predicted gene, 53749 Neighboring gene centromere protein O Neighboring gene ubiquitin associated protein 2-like pseudogene Neighboring gene predicted gene, 29696 Neighboring gene nuclear receptor coactivator 1 Neighboring gene STARR-seq mESC enhancer starr_31441 Neighboring gene STARR-seq mESC enhancer starr_31442 Neighboring gene aurora kinase A pseudogene Neighboring gene STARR-seq mESC enhancer starr_31447 Neighboring gene predicted gene, 51963

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Related articles in PubMed

  1. Mutagenesis of diploid mammalian genes by gene entrapment. Lin Q, et al. Nucleic Acids Res, 2006. PMID 17062627, Free PMC Article
  2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables peptidyl-tRNA hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Preferred Names
putative peptidyl-tRNA hydrolase PTRHD1
Names
peptidyl-tRNA hydrolase domain-containing protein 1
NP_001191841.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204912.2 → NP_001191841.1  putative peptidyl-tRNA hydrolase PTRHD1

    See identical proteins and their annotated locations for NP_001191841.1

    Status: VALIDATED

    Source sequence(s)
    AC162932
    Consensus CDS
    CCDS56829.1
    UniProtKB/Swiss-Prot
    D3Z4S3
    Related
    ENSMUSP00000137070.2, ENSMUST00000179139.3
    Conserved Domains (1) summary
    cl19212
    Location:25 → 139
    PTH2_family; Peptidyl-tRNA hydrolase, type 2 (PTH2)_like . Peptidyl-tRNA hydrolase activity releases tRNA from the premature translation termination product peptidyl-tRNA. Two structurally different enzymes have been reported to encode such activity, Pth present in ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    4284013..4290123
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D3Z4S3.1 GenPept UniProtKB/Swiss-Prot:D3Z4S3

Gene LinkOut

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