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ARHGEF39 Rho guanine nucleotide exchange factor 39 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 696846, updated on 16-Apr-2026
Official Symbol
ARHGEF39provided by VGNC
Official Full Name
Rho guanine nucleotide exchange factor 39provided by VGNC
Primary source
VGNC:VGNC:69912
See related
Ensembl:ENSMMUG00000016323
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
C9orf100; C15H9orf100
Orthologs
all
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Try the new Transcripts and proteins table
See ARHGEF39 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 15 NC_133420.1 (64021908..64038659)
103 previous assembly Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (48528259..48546984)

Chromosome 15 - NC_133420.1Genomic Context describing neighboring genes Neighboring gene talin 1 Neighboring gene tropomyosin 2 Neighboring gene carbonic anhydrase 9 Neighboring gene coiled-coil domain containing 107 Neighboring gene uncharacterized LOC144334642 Neighboring gene uncharacterized LOC106993705 Neighboring gene signaling threshold regulating transmembrane adaptor 1 Neighboring gene CD72 molecule

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
rho guanine nucleotide exchange factor 39
Names
Rho guanine nucleotide exchange factor (GEF) 39
vav-like protein C9orf100

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204918.3 → NP_001191847.2  rho guanine nucleotide exchange factor 39

    Status: PROVISIONAL

    Source sequence(s)
    JBMGST020000015
    UniProtKB/TrEMBL
    F7HL50, H9Z1Z8
    Related
    ENSMMUP00000039456.2, ENSMMUT00000046416.3
    Conserved Domains (2) summary
    smart00233
    Location:228 → 331
    PH; Pleckstrin homology domain
    cl02571
    Location:27 → 195
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133420.1 Reference T2T-MMU8v2.0

    Range
    64021908..64038659
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_077965022.1 → XP_077821148.1  rho guanine nucleotide exchange factor 39 isoform X2

  2. XM_028834233.2 → XP_028690066.1  rho guanine nucleotide exchange factor 39 isoform X2

    Conserved Domains (2) summary
    smart00233
    Location:192 → 295
    PH; Pleckstrin homology domain
    cl02571
    Location:6 → 159
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  3. XM_077965023.1 → XP_077821149.1  rho guanine nucleotide exchange factor 39 isoform X3

  4. XM_077965025.1 → XP_077821151.1  rho guanine nucleotide exchange factor 39 isoform X5

  5. XM_015117340.3 → XP_014972826.2  rho guanine nucleotide exchange factor 39 isoform X1

    Conserved Domains (2) summary
    smart00233
    Location:228 → 331
    PH; Pleckstrin homology domain
    cl02571
    Location:27 → 195
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  6. XM_015117341.3 → XP_014972827.2  rho guanine nucleotide exchange factor 39 isoform X4

    UniProtKB/TrEMBL
    G7NFD5
    Conserved Domains (2) summary
    smart00233
    Location:185 → 288
    PH; Pleckstrin homology domain
    cl02571
    Location:27 → 182
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
Nucleotide Protein
Heading Accession and Version

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