U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ddx51 DEAD box helicase 51 [ Mus musculus (house mouse) ]

Gene ID: 69663, updated on 11-Apr-2024

Summary

Official Symbol
Ddx51provided by MGI
Official Full Name
DEAD box helicase 51provided by MGI
Primary source
MGI:MGI:1916913
See related
Ensembl:ENSMUSG00000029504 AllianceGenome:MGI:1916913
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310061O04Rik
Summary
Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to act upstream of or within rRNA processing. Predicted to be active in nucleus. Is expressed in embryo. Orthologous to human DDX51 (DEAD-box helicase 51). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 7.5), CNS E11.5 (RPKM 7.0) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
5 F; 5 53.69 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (110801298..110810885)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (110653432..110663019)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 9 Neighboring gene STARR-seq mESC enhancer starr_13961 Neighboring gene NOC4 like Neighboring gene microRNA 7026 Neighboring gene E1A binding protein p400 Neighboring gene predicted gene, 22716

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ATP-dependent RNA helicase DDX51
Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEAD box protein 51
NP_081432.2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027156.3NP_081432.2  ATP-dependent RNA helicase DDX51

    See identical proteins and their annotated locations for NP_081432.2

    Status: VALIDATED

    Source sequence(s)
    BC060646, BY010157
    Consensus CDS
    CCDS19528.1
    UniProtKB/Swiss-Prot
    Q3U7M2, Q6P9R1
    Related
    ENSMUSP00000031478.6, ENSMUST00000031478.6
    Conserved Domains (3) summary
    PRK11192
    Location:176639
    PRK11192; ATP-dependent RNA helicase SrmB; Provisional
    pfam00271
    Location:462573
    Helicase_C; Helicase conserved C-terminal domain
    cl21455
    Location:176421
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    110801298..110810885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_880400.3 RNA Sequence