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NBN nibrin [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 695912, updated on 16-Jun-2026
Official Symbol
NBNprovided by VGNC
Official Full Name
nibrinprovided by VGNC
Primary source
VGNC:VGNC:75134
Locus tag
EGK_19107
See related
Ensembl:ENSMMUG00000014519
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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See NBN in Genome Data Viewer
Location:
chromosome: 8
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 8 NC_133413.1 (100391936..100441456, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (90329046..90378430, complement)

Chromosome 8 - NC_133413.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999849 Neighboring gene U6 spliceosomal RNA Neighboring gene oxidative stress induced growth inhibitor family member 2 Neighboring gene 2,4-dienoyl-CoA reductase 1 Neighboring gene uncharacterized LOC144330816

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic G2 DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Mre11 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
nibrin

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001265739.1 → NP_001252668.1  nibrin

    See identical proteins and their annotated locations for NP_001252668.1

    Status: PROVISIONAL

    Source sequence(s)
    JV565128
    UniProtKB/TrEMBL
    F6Q6E5, G7MZQ7, H9FUS2, I2CU28
    Related
    ENSMMUP00000032056.3, ENSMMUT00000038965.3
    Conserved Domains (4) summary
    cd00027
    Location:114 → 182
    BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
    cd00060
    Location:1 → 109
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    pfam08599
    Location:683 → 745
    Nbs1_C; DNA damage repair protein Nbs1
    pfam16508
    Location:216 → 325
    NIBRIN_BRCT_II; Second BRCT domain on Nijmegen syndrome breakage protein

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133413.1 Reference T2T-MMU8v2.0

    Range
    100391936..100441456 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_077942307.1 → XP_077798433.1  nibrin isoform X1

    UniProtKB/TrEMBL
    F6Q6E5, H9FUS2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Research Materials