Format

Send to:

Choose Destination

Tnfsf13 tumor necrosis factor (ligand) superfamily, member 13 [ Mus musculus (house mouse) ]

Gene ID: 69583, updated on 23-Jun-2021

Summary

Official Symbol
Tnfsf13provided by MGI
Official Full Name
tumor necrosis factor (ligand) superfamily, member 13provided by MGI
Primary source
MGI:MGI:1916833
See related
Ensembl:ENSMUSG00000089669
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TA; TRD; April; Tall2; Trdl1; Tnlg7b; 2310026N09Rik
Expression
Broad expression in lung adult (RPKM 9.6), colon adult (RPKM 8.2) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tnfsf13 in Genome Data Viewer
Location:
11; 11 B3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (69573403..69576380, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (69682577..69685554, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69496079..69499056, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4A1 Neighboring gene predicted gene, 22988 Neighboring gene SUMO/sentrin specific peptidase 3 Neighboring gene tumor necrosis factor (ligand) superfamily, member 13, opposite strand Neighboring gene tumor necrosis factor (ligand) superfamily, membrane-bound member 13 Neighboring gene tumor necrosis factor (ligand) superfamily, member 12 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Readthrough Tnfsfm13

Readthrough gene: Tnfsfm13, Included gene: Tnfsf12

Homology

Clone Names

  • MGC106105

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
enables receptor ligand activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tumor necrosis factor ligand superfamily member 13
Names
a proliferation-inducing ligand
tumor necrosis factor ligand 7b

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159505.1NP_001152977.1  tumor necrosis factor ligand superfamily member 13 isoform 2

    See identical proteins and their annotated locations for NP_001152977.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (2) lacks one internal aa, compared to isoform 1.
    Source sequence(s)
    AK009514, AK134028, AL603707
    Consensus CDS
    CCDS48827.1
    UniProtKB/Swiss-Prot
    Q9D777
    UniProtKB/TrEMBL
    Q5F2A4
    Related
    ENSMUSP00000018896.8, ENSMUST00000018896.14
    Conserved Domains (1) summary
    cd00184
    Location:108238
    TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
  2. NM_023517.2NP_076006.2  tumor necrosis factor ligand superfamily member 13 isoform 1

    See identical proteins and their annotated locations for NP_076006.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK009514, AK134028, BY463961
    UniProtKB/Swiss-Prot
    Q9D777
    UniProtKB/TrEMBL
    Q5F2A4
    Conserved Domains (1) summary
    cd00184
    Location:108239
    TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    69573403..69576380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center