Format

Send to:

Choose Destination

Bst2 bone marrow stromal cell antigen 2 [ Mus musculus (house mouse) ]

Gene ID: 69550, updated on 23-Jun-2021

Summary

Official Symbol
Bst2provided by MGI
Official Full Name
bone marrow stromal cell antigen 2provided by MGI
Primary source
MGI:MGI:1916800
See related
Ensembl:ENSMUSG00000046718
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GRE; Bst-; GREG; Bst-2; CD317; C87040; DAMP-1; 2310015I10Rik
Expression
Broad expression in ovary adult (RPKM 548.4), liver adult (RPKM 286.5) and 17 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Bst2 in Genome Data Viewer
Location:
8; 8 B3.3
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (71986899..71990116, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (71534255..71537472, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (74058158..74061336, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene GTP binding protein 3 Neighboring gene plasmalemma vesicle associated protein Neighboring gene coiled-coil domain containing 194 Neighboring gene 14-3-3 protein sigma-like Neighboring gene multivesicular body subunit 12A Neighboring gene transmembrane protein 221

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables metalloendopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metalloendopeptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in defense response to virus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in defense response to virus ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in innate immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in innate immune response ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of intracellular transport of viral material IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of intracellular transport of viral material IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of intracellular transport of viral material ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of plasmacytoid dendritic cell cytokine production ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of viral genome replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of viral genome replication ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
involved_in response to interferon-alpha IDA
Inferred from Direct Assay
more info
PubMed 
involved_in response to interferon-beta IDA
Inferred from Direct Assay
more info
PubMed 
involved_in response to interferon-gamma IDA
Inferred from Direct Assay
more info
PubMed 
involved_in response to virus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in response to virus ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in multivesicular body ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
bone marrow stromal antigen 2
Names
DAMP-1 protein homolog
HM1.24 antigen
tetherin

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198095.3NP_932763.1  bone marrow stromal antigen 2

    See identical proteins and their annotated locations for NP_932763.1

    Status: VALIDATED

    Source sequence(s)
    BC087949, BY166837
    Consensus CDS
    CCDS22397.1
    UniProtKB/Swiss-Prot
    Q8R2Q8
    Related
    ENSMUSP00000051921.8, ENSMUST00000051672.9
    Conserved Domains (1) summary
    pfam16716
    Location:54141
    BST2; Bone marrow stromal antigen 2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    71986899..71990116 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center