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EIF2D eukaryotic translation initiation factor 2D [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 695274, updated on 10-Feb-2026
Official Symbol
EIF2Dprovided by VGNC
Official Full Name
eukaryotic translation initiation factor 2Dprovided by VGNC
Primary source
VGNC:VGNC:72258
See related
Ensembl:ENSMMUG00000002528
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
LGTN
Annotation information
Note: The name of this locus was changed from ligatin to eukaryotic translation initiation factor 2D based on the gene characterization of the human ortholog reported in PMID:20566627. [18 Aug 2011]
Orthologs
all
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See EIF2D in Genome Data Viewer
Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 1 NC_133406.1 (64336100..64356742, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (64098472..64119183, complement)

Chromosome 1 - NC_133406.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC144341418 Neighboring gene Ras association domain family member 5 Neighboring gene uncharacterized LOC144341440 Neighboring gene uncharacterized LOC144341439 Neighboring gene uncharacterized LOC144341443 Neighboring gene uncharacterized LOC144341449 Neighboring gene dual specificity tyrosine phosphorylation regulated kinase 3 Neighboring gene small ribosomal subunit protein uS11 pseudogene Neighboring gene MAPK activated protein kinase 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in formation of translation preinitiation complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
eukaryotic translation initiation factor 2D
Names
ligatin

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266770.1 → NP_001253699.1  eukaryotic translation initiation factor 2D

    See identical proteins and their annotated locations for NP_001253699.1

    Status: PROVISIONAL

    Source sequence(s)
    JV044182
    UniProtKB/TrEMBL
    G7MER3, I0FIH7
    Related
    ENSMMUP00000065635.1, ENSMMUT00000102528.1
    Conserved Domains (4) summary
    cd11608
    Location:490 → 574
    eIF2D_C; C-terminal domain of eIF2D and related proteins
    cd11610
    Location:6 → 81
    eIF2D_N; N-terminal domain of eIF2D and related proteins
    COG2016
    Location:7 → 178
    Tma20; Predicted ribosome-associated RNA-binding protein Tma20, contains PUA domain [Translation, ribosomal structure and biogenesis]
    cl00607
    Location:68 → 174
    PUA; PUA domain

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133406.1 Reference T2T-MMU8v2.0

    Range
    64336100..64356742 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028828005.2 → XP_028683838.1  eukaryotic translation initiation factor 2D isoform X2

    UniProtKB/TrEMBL
    F7GX41
    Conserved Domains (3) summary
    cd11608
    Location:366 → 450
    eIF2D_C; C-terminal domain of eIF2D and related proteins
    pfam17832
    Location:2 → 90
    Pre-PUA; Pre-PUA-like domain
    cd21156
    Location:92 → 173
    PUA_eIF2d-like; PUA RNA-binding domain of eukaryotic translation initiation factor 2D and similar proteins

  2. XM_078004909.1 → XP_077861035.1  eukaryotic translation initiation factor 2D isoform X1

    UniProtKB/TrEMBL
    G7MER3
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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